Brief Article
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World J Gastroenterol. Jun 28, 2013; 19(24): 3810-3818
Published online Jun 28, 2013. doi: 10.3748/wjg.v19.i24.3810
Quality of life following laparoscopic Nissen fundoplication: Assessing short-term and long-term outcomes
Ilmo Kellokumpu, Markku Voutilainen, Caj Haglund, Martti Färkkilä, Peter J Roberts, Hannu Kautiainen
Ilmo Kellokumpu, Department of Surgery, Central Hospital of Central Finland, 40620 Jyväskylä, Finland
Markku Voutilainen, Department of Gastroenterology, Central Hospital of Central Finland, 40620 Jyväskylä, Finland
Caj Haglund, Department of Surgery, Helsinki University Central Hospital, 00029 Helsinki, Finland
Martti Färkkilä, Division of Gastroenterology, Department of Internal Medicine, Helsinki University Central Hospital, 00029 Helsinki, Finland
Peter J Roberts, Department of Surgery, Turku University Hospital, 20520 Turku, Finland
Hannu Kautiainen, Biostatistician, Unit of Primary Health Care, Helsinki University Hospital, 00029 Helsinki, Finland
Hannu Kautiainen, Department of General Practice, Primary Health Care Unit, Turku University Hospital, 20520 Turku, Finland
Author contributions: All authors contributed equally to this work and participated to the design of the study, data acquisition, analysis and writing of the manuscript; all authors approved the final manuscript.
Supported by EVO-funding of the Central Hospital of Central Finland
Correspondence to: Ilmo Kellokumpu, MD, PhD, Chief, Department of Surgery, Central Hospital of Central Finland, Keskussairaalantie 19, 40620 Jyväskylä, Finland. ilmo.kellokumpu@ksshp.fi
Telephone: +358-14-2691811 Fax: +358-14-2692929
Received: January 3, 2013
Revised: March 31, 2013
Accepted: April 9, 2013
Published online: June 28, 2013
Processing time: 176 Days and 5.9 Hours
Core Tip

Core tip: Current evidence suggests that laparoscopic fundoplication is more effective than medical therapy for the short- and medium-term treatment of gastroesophageal reflux disease. This study examined short-term and long-term outcomes after laparoscopic Nissen fundoplication. Short-term outcomes were assessed by symptom response, side effects of surgery, endoscopy and the patient’s perception of overall success. Long-term outcomes were examined by addressing multiple domains affected by the operation including reflux symptoms, side effects of surgery, durability of antireflux surgery, selective objective testing, need for additional medical or surgical treatment, the patient’s perception of overall success, and long-term quality of life.