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World J Gastroenterol. Jun 21, 2013; 19(23): 3699-3702
Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3699
Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3699
Esophageal mucosal metastasis from adenocarcinoma of the distal stomach
Sung-Ho Ki, Division of Gastroenterology, Department of Internal Medicine, Pohang St. Mary’s Hospital, Pohang 790-825, South Korea
Seok Jeong, Don Haeng Lee, Jung Il Lee, Kye Sook Kwon, Hyung Gil Kim, Yong Woon Shin, Division of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 400-711, South Korea
In Suh Park, Department of Pathology, Inha University School of Medicine, Incheon 400-711, South Korea
Don Haeng Lee, Center for Advanced Medical Education by BK21 Project, Inha University School of Medicine, Utah-Inha DDS and Advanced Therapeutics Research Center, Incheon 400-711, South Korea
Author contributions: Ki Sh and Jeong S designed the report; Ki SH, Jeong S and Lee DH were attending doctors for the patient; Park IS performed pathologic examinations; Ki SH, Jeong S and Kim HG performed image diagnosis; Lee JI, Shin YW and Kwon KS organized the report; Ki SH wrote paper.
Correspondence to: Seok Jeong, MD, Division of Gastroenterology, Department of Internal Medicine, Inha University Hospital, 7-206, 3-Ga, Sinheung-Dong, Jung-Gu, Incheon 400-711, South Korea. inos@inha.ac.kr
Telephone: +82-32-8902548 Fax: +82-32-8902549
Received: February 4, 2013
Revised: March 22, 2013
Accepted: April 27, 2013
Published online: June 21, 2013
Processing time: 136 Days and 6.4 Hours
Revised: March 22, 2013
Accepted: April 27, 2013
Published online: June 21, 2013
Processing time: 136 Days and 6.4 Hours
Core Tip
Core tip: I believe the paper may be of particular interest to your readers because the reason is as follows. First, there has been rarity of case reports about esophageal metastasis from gastric cancer without any evidence of lymphatic involvement or direct spread from the primary lesion. Second, gastroesophageal reflux of cancer cells could be one of the possible metastatic pathways for metastasis of esophagus from an adenocarcinoma of the stomach, and this case proves the possibility of direct implantation of gastric adenocarcinoma cells refluxed on esophagus.