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World J Gastroenterol. Jun 21, 2013; 19(23): 3555-3561
Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3555
Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3555
Heme oxygenase-1 and gut ischemia/reperfusion injury: A short review
Yu-Feng Liao, Department of Laboratory Medicine, Ningbo No. 2 Hospital, Ningbo 315010, Zhejiang Province, China
Wei Zhu, Xiao Zhu, Molecular Pathology Platform, Key Laboratory of Molecular Diagnosis, Guangdong Medical College, Dongguan 523808, Guangdong Province, China
Dong-Pei Li, Institute of Molecular Medicine and Genetics, Georgia Health Sciences University, Augusta, GA 30912, United States
Author contributions: Zhu X, Liao YF and Zhu W reviewed the literature and prepared the manuscript; Zhu X drafted the figure; Li DP reviewed the final version of the paper.
Supported by Natural Science Foundation of Ningbo City, No. 2012A610194; National Natural Science Foundation of China, No. 81071697; Natural Science Foundation of Guangdong Province, No. S2011040003694
Correspondence to: Xiao Zhu, PhD, Molecular Pathology Platform, Key Laboratory of Molecular Diagnosis, Guangdong Medical College, No. 1 Xincheng Road, Dongguan 523808, Guangdong Province, China. bioxzhu@yahoo.com
Telephone: +86-769-22896373 Fax: +86-769-22896373
Received: January 2, 2013
Revised: March 15, 2013
Accepted: April 10, 2013
Published online: June 21, 2013
Processing time: 169 Days and 13 Hours
Revised: March 15, 2013
Accepted: April 10, 2013
Published online: June 21, 2013
Processing time: 169 Days and 13 Hours
Core Tip
Core tip: In this review, we focused on the heme oxygenase (HO)-1 system and its possible roles and mechanisms in gut ischemia/reperfusion (I/R) injury studied to date. This review, for the first time, reviews in detail the relationship between HO-1 and gut I/R injury.