Copyright
©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. May 28, 2013; 19(20): 3134-3142
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.3134
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.3134
Nonalcoholic fatty liver disease and microvascular complications in type 2 diabetes
Wen-Shan Lv, Rui-Xia Sun, Yan-Yan Gao, Rong-Fang Pan, Li Li, Jing Wang, Yu-Xin Xian, Cai-Xia Cao, the Department of Internal Medicine, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266100, Shandong Province, China
Jun-Ping Wen, Ming Zheng, Fujian Provincial Hospital, Fujian Provincial Geriatric Hospital, Fujian Medical University, Fuzhou 350001, Fujian Province, China
Author contributions: Lv WS and Sun RX contributed equally to this work; Lv WS, Gao YY and Zheng M designed the research; Pan RF, Wen JP, Li L, Wang J, Xian YX and Cao CX performed the research; Lv WS analyzed the data and wrote the manuscript.
Supported by Natural Science Foundation of China, No. 81270939, No. 30900510 and No. 81170774; and Natural Science Foundation of Fujian Province, No. 2011J01127
Correspondence to: Ming Zheng, MD, Fujian Provincial Hospital, Fujian Provincial Geriatric Hospital, Fujian Medical University, No. 88 Jiaotong Road, Fuzhou 350001, Fujian Province, China. mingzhengcn@yeah.net
Telephone: +86-591-87557768 Fax: +86-591-87532356
Received: November 28, 2012
Revised: March 6, 2013
Accepted: March 23, 2013
Published online: May 28, 2013
Processing time: 180 Days and 22.6 Hours
Revised: March 6, 2013
Accepted: March 23, 2013
Published online: May 28, 2013
Processing time: 180 Days and 22.6 Hours
Core Tip
Core tip: Nonalcoholic fatty liver disease (NAFLD) and diabetic microangiopathy complications represent important burdens for patients with type 2 diabetes mellitus (T2DM). However based on the finding that the prevalence of NAFLD was negatively correlated with age and duration of T2DM, we suggest that NAFLD is benign process and efforts should be directed at strengthening early diagnosis, intensive blood glucose and pressure control, and effective dyslipidemia correction to prevent and minimize occurrence of NAFLD.