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World J Gastroenterol. May 28, 2013; 19(20): 2985-2996
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.2985
Published online May 28, 2013. doi: 10.3748/wjg.v19.i20.2985
Role of microRNAs in the immune system, inflammation and cancer
Jennifer Raisch, Arlette Darfeuille-Michaud, Hang Thi Thu Nguyen, M2iSH, UMR 1071 Inserm, University of Auvergne, 63000 Clermont-Ferrand, France
Jennifer Raisch, Arlette Darfeuille-Michaud, Hang Thi Thu Nguyen, INRA USC 2018, 63000 Clermont-Ferrand, France
Arlette Darfeuille-Michaud, Centre Hospitalier Universitaire, 63000 Clermont-Ferrand, France
Author contributions: Raisch J and Nguyen HTT wrote the paper; Darfeuille-Michaud A supervised the manuscript.
Supported by The Ministère de la Recherche et de la Technologie (JE2526, France), Inserm and University of Auvergne (UMR1071), INRA (USC-2018); Grants from the Association François Aupetit (AFA to Arlette Darfeuille-Michaud), and the European Union FP7 People Marie Curie International Incoming Fellowship (IIF to Hang Nguyen)
Correspondence to: Hang Thi Thu Nguyen, PhD, Assistant Professor, M2iSH, UMR 1071 Inserm, University of Auvergne, 28 place Henri Dunant, 63000 Clermont-Ferrand, France. hang.nguyen@udamail.fr
Telephone: +33-4-73178372 Fax: +33-4-73178371
Received: January 24, 2013
Revised: March 29, 2013
Accepted: April 10, 2013
Published online: May 28, 2013
Revised: March 29, 2013
Accepted: April 10, 2013
Published online: May 28, 2013
Core Tip
Core tip: MicroRNAs (miRNAs), a key class of gene expression regulators, have emerged as crucial players in various biological processes such as cellular proliferation and differentiation, development and apoptosis. A better understanding of the function of miRNAs is providing new insights into the molecular basis of human pathologies, and new biomarkers for disease diagnosis and therapy.