Brief Article
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World J Gastroenterol. May 7, 2013; 19(17): 2709-2713
Published online May 7, 2013. doi: 10.3748/wjg.v19.i17.2709
Difference in DRB1* gene polymorphisms between Han and Uyghur ulcerative colitis patients in China
Ayinuer Aheman, Feng Gao, Aihemaijiang Kuerbanjiang, Yue-Xian Li, Mireayi Abuduhadeer
Ayinuer Aheman, Feng Gao, Aihemaijiang Kuerbanjiang, Yue-Xian Li, Mireayi Abuduhadeer, Department of Gastroenterology, People’s Hospital of Xinjiang Uyghur Autonomous Region, Urumqi 830001, Xinjiang Uyghur Autonomous Region, China
Author contributions: Aheman A designed the study, wrote and revised the manuscript; Kuerbanjiang A, Li YX, Abuduhadeer M analyzed and interpreted the data; Gao F acquired funding, and revised the manuscript critically for important intellectual content; supervised the study; and all authors read and approved the final version to be published.
Supported by Natural Science Foundation of Xinjiang Uyghur Autonomous Region of China, No. 2009211A26
Correspondence to: Feng Gao, Professor, Chief, Department of Gastroenterology, People’s Hospital of Xinjiang Uyghur Autonomous Region, Tianchi str 91, Urumqi 830001, Xinjiang Uyghur Autonomous Region, China. xjgf@sina.com
Telephone: + 86-991-8563342 Fax: +86-991-8565302
Received: November 18, 2012
Revised: February 28, 2013
Accepted: March 6, 2013
Published online: May 7, 2013
Processing time: 178 Days and 0.1 Hours
Core Tip

Core tip: This study evaluated the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients residing in the Xinjiang Uyghur Autonomous Region of China. The authors found that polymorphism of the HLA-DRB1* gene differed between the Han and Uyghur patients with UC. Polymorphism of the HLA-DRB1 gene may contribute to the clinical heterogeneity of UC between Han and Uyghur UC patients in North-West China.