Case Report
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World J Gastroenterol. Apr 28, 2013; 19(16): 2569-2573
Published online Apr 28, 2013. doi: 10.3748/wjg.v19.i16.2569
Portal vein stenosis after pancreatectomy following neoadjuvant chemoradiation therapy for pancreatic cancer
Yosuke Tsuruga, Hirofumi Kamachi, Kenji Wakayama, Tatsuhiko Kakisaka, Hideki Yokoo, Toshiya Kamiyama, Akinobu Taketomi
Yosuke Tsuruga, Hirofumi Kamachi, Kenji Wakayama, Tatsuhiko Kakisaka, Hideki Yokoo, Toshiya Kamiyama, Akinobu Taketomi, Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
Author contributions: All authors gave substantial contributions to acquisition, analysis and interpretation of data and participated in writing the paper; Taketomi A gave final approval of the version to be published.
Correspondence to: Yosuke Tsuruga, MD, PhD, Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan. ytsuruga@med.hokudai.ac.jp
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Received: December 5, 2012
Revised: February 8, 2013
Accepted: March 8, 2013
Published online: April 28, 2013
Processing time: 147 Days and 22.9 Hours
Core Tip

Core tip: Intraoperative radiation therapy for pancreatic cancer with/without portal vein (PV) resection is reported to be associated with PV stenosis. However, there has been no report of PV stenosis after pancreatectomy following neoadjuvant chemoradiation therapy (NACRT). Here we report the cases of three patients with PV stenosis after pancreatectomy and PV resection following gemcitabine-based NACRT for pancreatic cancer and their successful treatment with stent placement. We have performed pancreatectomy with PV resection following NACRT in 8 patients with borderline resectable pancreatic cancer since 2005. The ratio of post-operative PV stenosis is 37.5% in this series.