Original Article
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Dec 28, 2012; 18(48): 7166-7174
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7166
Oridonin induces apoptosis in gastric cancer through Apaf-1, cytochrome c and caspase-3 signaling pathway
Ke-Wang Sun, Ying-Yu Ma, Tian-Pei Guan, Ying-Jie Xia, Chang-Ming Shao, Le-Gao Chen, Ya-Jun Ren, Hai-Bo Yao, Qiong Yang, Xu-Jun He
Ke-Wang Sun, Qiong Yang, Department of Thyroid and Breast Surgery, Zhejiang Provincial People’s Hospital, Hangzhou 310014, Zhejiang Province, China
Ying-Yu Ma, Ying-Jie Xia, Xu-Jun He, Key Laboratory of Gastroenterology of Zhejiang Province, Zhejiang Provincial People’s Hospital, Hangzhou 310014, Zhejiang Province, China
Tian-Pei Guan, Chang-Ming Shao, Le-Gao Chen, Hai-Bo Yao, Surgical Department, Wenzhou Medical College, Wenzhou 310025, Zhejiang Province, China
Ya-Jun Ren, Surgical Department, Zhejiang Chinese Medical University, Hangzhou 310014, Zhejiang Province, China
Author contributions: Sun KW and He XJ designed research; Ma YY, Guan TP, Xia YJ, Shao CM, Chen LG, Ren YJ, Yao HB and He XJ performed the majority of experiments; Xia YJ, Shao CM, Ren YJ and Yang Q provided vital reagents and analytical tools; Sun KW, Guan TP and He XJ analyzed data; and Ma YY and He XJ wrote the paper.
Supported by Medical and Health Research Foundation of Zhejiang Province, No. 2009B019
Correspondence to: Xu-Jun He, Research Associate, Key Laboratory of Gastroenterology of Zhejiang Province, Zhejiang Provincial People’s Hospital, No. 158, Shangtang Road, Hangzhou 310014, Zhejiang Province, China. hxj0105099@126.com
Telephone: +86-571-85893781 Fax: +86-571-85131448
Received: March 30, 2012
Revised: September 21, 2012
Accepted: October 16, 2012
Published online: December 28, 2012
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