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World J Gastroenterol. Aug 7, 2011; 17(29): 3407-3419
Published online Aug 7, 2011. doi: 10.3748/wjg.v17.i29.3407
Published online Aug 7, 2011. doi: 10.3748/wjg.v17.i29.3407
Identification of methylation profile of HOX genes in extrahepatic cholangiocarcinoma
Yi Shu, Bing Wang, Ji Wang, Jian-Ming Wang, Sheng-Quan Zou, General Surgery Department of Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China
Author contributions: Shu Y conducted the Methyl-DNA immunoprecipitation, bisulfite-PCR, treatment with 5-Aza-2’-deoxycytidine and statistical analysis and drafted the manuscript; Wang B did immunofluorescence assays, statistical analysis and drafted the manuscript; Wang J and Wang JM participated in the statistical analysis and drafted the manuscript. Zou SQ conceived and designed the studies; all authors discussed the results, commented on the manuscript, read and approved the final manuscript.
Supported by The grant for “Development of Novel Nano-Drug Delivery System Loaded with Traditional Chinese Anticancer Medicine for the Targeted Therapy of Malignant Tumors” issued by the Chinese Ministry of Science and Technology, Grant No. 2010DFA31870
Correspondence to: Sheng-Quan Zou, Professor, General Surgery Department of Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. sqzou05@yahoo.com.cn
Telephone: +86-27-83662688 Fax: +86-27-83662398
Received: March 11, 2011
Revised: May 17, 2011
Accepted: May 24, 2011
Published online: August 7, 2011
Revised: May 17, 2011
Accepted: May 24, 2011
Published online: August 7, 2011
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