Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome

doi:10.3748/wjg.v16.i36.4532

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Sep 28, 2010 (publication date) through May 7, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2010; 16(36): 4532-4540
Published online Sep 28, 2010. doi: 10.3748/wjg.v16.i36.4532

Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome

Erja Malinen, Lotta Krogius-Kurikka, Anna Lyra, Janne Nikkilä, Anne Jääskeläinen, Teemu Rinttilä, Terttu Vilpponen-Salmela, Atte Johannes von Wright, Airi Palva

Erja Malinen, Lotta Krogius-Kurikka, Janne Nikkilä, Airi Palva, Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00014 Helsinki, Finland

Anna Lyra, Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00014 Helsinki, Finland; Danisco Sweeteners, Health and Nutrition, 02460 Kantvik, Finland

Anne Jääskeläinen, Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland

Teemu Rinttilä, Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, 00014 Helsinki, Finland; Alimetrics Ltd., Koskelontie 19 B, 02920 Espoo, Finland

Terttu Vilpponen-Salmela, Kuopio Harjula Hospital, 70101 Kuopio, Finland

Atte Johannes von Wright, Department of Biosciences, University of Eastern Finland, 70211 Kuopio, Finland

Author contributions: Malinen E, Krogius-Kurikka L, Jääskeläinen A, Vilpponen-Salmela T, von Wright AJ and Palva A designed the research protocol; Vilpponen-Salmela T recruited the patients; Jääskeläinen A organized the collection of IBDQ questionnaires and performed the primary data analysis of the questionnaires; Krogius-Kurikka L, Lyra A and Rinttilä T performed the experiments; Malinen E and Nikkilä J conducted the computational data analyses; Malinen E, Krogius-Kurikka L and Lyra A wrote the manuscript and all authors made corrections to and approved the final version.

Supported by The Finnish Funding Agency for Technology and Innovation (Tekes grant No. 40039/03), the Finnish Graduate School on Applied Biosciences and the Centre of Excellence on Microbial Food Safety Research, Academy of Finland

Correspondence to: Airi Palva, Professor, Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, PO Box 66, 00014 Helsinki, Finland. airi.palva@helsinki.fi

Telephone: +358-9-19157058 Fax: +358-9-19157033

Received: March 5, 2010
Revised: May 5, 2010
Accepted: May 12, 2010
Published online: September 28, 2010

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