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World J Gastroenterol. Mar 28, 2010; 16(12): 1430-1435
Published online Mar 28, 2010. doi: 10.3748/wjg.v16.i12.1430
COX-2 in liver, from regeneration to hepatocarcinogenesis: What we have learned from animal models?
Paloma Martín-Sanz, Rafael Mayoral, Marta Casado, Lisardo Boscá
Paloma Martín-Sanz, Rafael Mayoral, Marta Casado, Lisardo Boscá, Biomedical Network Center for the Study of Hepatic and Digestive Diseases (CIBERehd), Villarroel 170, Barcelona 08036, Spain
Paloma Martín-Sanz, Rafael Mayoral, Lisardo Boscá, Department of Metabolism and Cell Signaling, Institute of Biomedical Research “Alberto Sols” (CSIC-UAM), Arturo Duperier 4, Madrid 28029, Spain
Marta Casado, Department of Pathology and Molecular and Cellular Therapy, Institute of Biomedicine of Valencia (IBV-CSIC), Jaume Roig 11, Valencia 46010, Spain
Author contributions: Martín-Sanz P and Boscá L contributed equally to writing of the paper; Mayoral R and Casado M performed the experiments in support of the work. All authors analyzed the data and discussed the biological relevance of the animal models.
Supported by Grant BFU2008-02161 and SAF2007-60551 from MICINN, S-BIO-0283/2006 from Comunidad de Madrid and FIS-RECAVA RD06/0014/0025. RECAVA and CIBERehd are funded by the Instituto de Salud Carlos III
Correspondence to: Dr. Lisardo Boscá, Department of Metabolism and Cell Signaling, Institute of Biomedical Research “Alberto Sols” (CSIC-UAM), Arturo Duperier 4, Madrid 28029, Spain. lbosca@iib.uam.es
Telephone: +34-91-4972747 Fax: +34-91-5854401
Received: December 17, 2009
Revised: January 15, 2010
Accepted: January 22, 2010
Published online: March 28, 2010
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