Copyright
©2010 Baishideng. All rights reserved.
World J Gastroenterol. Mar 14, 2010; 16(10): 1267-1273
Published online Mar 14, 2010. doi: 10.3748/wjg.v16.i10.1267
Published online Mar 14, 2010. doi: 10.3748/wjg.v16.i10.1267
Establishment of a new quantitative detection approach to adefovir-resistant HBV and its clinical application
Wei-Feng Zhao, You-Lin Shao, Liang-Yun Chen, Jin-Hua Wu, Yi-Ling Zhu, Jian-He Gan, Department of Infectious Diseases, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
Hui Xiong, Shanghai Laboratory of Disease and Health Genomics, Chinese National Human Genome Center, Shanghai 201203, China
Author contributions: Zhao WF performed the quantitative RT-PCR, direct sequencing analysis and wrote the manuscript; Shao YL and Chen LY performed the T-A cloning, quantitative RT-PCR and direct sequencing analysis, and wrote the manuscript; Wu JH collected the serum samples and clinical data; Zhu YL collected the serum samples; Gan JH coordinated the study; Xiong H contributed to the overall interpretation of data and participated in writing the manuscript.
Supported by The fund from Health Project of Jiangsu Province, No. H200711 and the AIDS, Hepatitis B and Other Infectious Diseases Prevention Program, No. 2009ZX10004-712
Correspondence to: Hui Xiong, PhD, Shanghai Laboratory of Disease and Health Genomics, Chinese National Human Genome Center, Shanghai 201203, China. xionghui@chgc.sh.cn
Telephone: +86-21-58554463 Fax: +86-21-58557486
Received: March 4, 2009
Revised: March 27, 2009
Accepted: April 3, 2009
Published online: March 14, 2010
Revised: March 27, 2009
Accepted: April 3, 2009
Published online: March 14, 2010
Core Tip