Deng Y, Jiang Y, Jiang T, Chen L, Mou HJ, Tuo BG, Shi GQ. Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1. World J Gastroenterol 2024; 30(5): 440-449 [PMID: 38414583 DOI: 10.3748/wjg.v30.i5.440]
Corresponding Author of This Article
Guo-Qing Shi, MM, Chief Doctor, Department of Gastroenterology, Digestive Disease Hospital, The Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563000, Guizhou Province, China. sgqing973@sina.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Feb 7, 2024; 30(5): 440-449 Published online Feb 7, 2024. doi: 10.3748/wjg.v30.i5.440
Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1
Yue Deng, Ya Jiang, Tong Jiang, Ling Chen, Hai-Jun Mou, Bi-Guang Tuo, Guo-Qing Shi
Yue Deng, Tong Jiang, Ling Chen, Hai-Jun Mou, Bi-Guang Tuo, Guo-Qing Shi, Department of Gastroenterology, Digestive Disease Hospital, The Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China
Yue Deng, Department of Gastroenterology, Guizhou Hospital of the First Affiliated Hospital, Sun Yat-sen University, Guiyang 550000, Guizhou Province, China
Ya Jiang, Department of Gastroenterology, Yinjiang Autonomous County People’s Hospital, Tongren 554300, Guizhou Province, China
Co-first authors: Yue Deng and Ya Jiang.
Author contributions: Deng Y and Jiang Y designed the research study and wrote the paper; Jiang Y, Mou HJ, and Shi GQ contributed to the surgical operations and provided clinical advice; Tuo BG supervised the study; Jiang T and Chen L contributed to the analysis and interpretation of the data; Shi GQ approved the final version of the article to be published.
Supported bythe Guizhou Provincial Science and Technology Program, No. [2020]4Y004.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Affiliated Hospital of Zunyi Medical University.
Informed consent statement: Patients were not required to give informed consent to participate in the study because the analysis used anonymous clinical data that were obtained after each patient agreed to the treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Qing Shi, MM, Chief Doctor, Department of Gastroenterology, Digestive Disease Hospital, The Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563000, Guizhou Province, China. sgqing973@sina.com
Received: October 3, 2023 Peer-review started: October 3, 2023 First decision: December 4, 2023 Revised: December 15, 2023 Accepted: January 11, 2024 Article in press: January 11, 2024 Published online: February 7, 2024 Processing time: 119 Days and 14.5 Hours
ARTICLE HIGHLIGHTS
Research background
During the treatment of type 1 gastric variceal hemorrhage (GOV1), endoscopic band ligation (EBL), endoscopic tissue adhesive injection (TAI) and endoscopic injection sclerotherapy can cause serious complications. Therefore, individualized treatment is urgently needed.
Research motivation
The optimal individualized therapy for patients with mild or moderate GOV1 has yet to be identified. It is important to choose the appropriate treatment modality according to the type, morphology and severity of varicose veins to further improve the treatment efficacy and minimize the incidence of associated complications. Thus, this new treatment will greatly reduce patient suffering.
Research objectives
We focused on comparing the differences between the EBL and TAI treatments. This study provides new ideas for the treatment of mild and moderate GOV1.
Research methods
This retrospective study compared the efficacy, safety and costs of EBL and TAI. A detailed comparison of the varicose-relief rate, operative time, operation success rate, mortality rate within 6 wk, rebleeding rate, 6-wk operation-related ulcer healing rate, complication rate and average operation cost was performed.
Research results
EBL has a higher one-time varix eradication rate, a higher 6-wk operation-related ulcer healing rate, a lower delayed rebleeding rate and a lower cost than TAI for mild to moderate GOV1.
Research conclusions
This study provides a new method for the treatment of mild to moderate GOV1:EBL.
Research perspectives
EBL has a higher one-time varix eradication rate, higher 6-wk operation-related ulcer healing rate, lower delayed rebleeding rate and lower cost than TAI for mild to moderate GOV1.
