Brief Reports
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 15, 2003; 9(10): 2350-2352
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2350
Experimental study of diode-laser induced thermocoagulation on hepatic tissue with scanner fiber tip
De-Fei Hong, Shu-You Peng, Song-Ying Li, Li-Min Tong
De-Fei Hong, Shu-You Peng, Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Song-Ying Li, Department of Pathology, Medical College of Zhejiang University, Hangzhou 310006, Zhejiang Province, China
Li-Min Tong, Department of Physics, State Key Laboratory of Silicon Marterial, Zhejiang University, Hangzhou 310027, Zhejiang Province, China
Author contributions: All authors contributed equally to the work.
Supported by the Youth Science Foundation of National 863 Laser Technique
Correspondence to: De-Fei Hong, Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, Zhejiang Province, China. hongdefi@mail.hz.zj.cn
Telephone: 13605700656
Received: December 22, 2002
Revised: February 6, 2003
Accepted: February 13, 2003
Published online: October 15, 2003
Abstract

AIM: To explore a safe, efficient, and cost-effective technique for local thermo-ablation of hepatic tumors.

METHODS: The livers of 16 healthy rabbits were thermocoagulated by diode-laser with a hand-made scanner fiber tip, 6 w for 10 min. At the same time, the temperature was measured at 5 and 10 mm from the laser tip. Liver function 7 d post-thermocoagulation was compared to pre-thermocoagulation. Pathological changes were also studied 1 month after laser thermocoagulation.

RESULTS: All the rabbits lived and the temperature of hepatic tissues at 0 mm, 5 mm, 10 mm from laser tip reached 96.39 ± 3.97 °C, 60.79 ± 6.21 °C, 46.10 ± 4.58 °C, respectively after 10 min thermocoagulation. There was no significant change in liver function. The hepatic thermocoagulated necrosis and the surrounding fibrosis was 26.0 mm in diameter. Light microscopy observation revealed no surviving cells in the coagulated area.

CONCLUSION: Hepatic tissue can be locally ablated safely and effectively by diode-laser with scanner fiber tip, and this technique may be a new method to treat hepatic tumors.

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