Multivariate regression analysis on early mortality after orthotopic liver transplantion

doi:10.3748/wjg.v8.i1.128

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Feb 15, 2002 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 15, 2002; 8(1): 128-130
Published online Feb 15, 2002. doi: 10.3748/wjg.v8.i1.128

Multivariate regression analysis on early mortality after orthotopic liver transplantion

Ye-Ben Qian, Gui-Hua Cheng, Jie-Fu Huang

Ye-Ben Qian, Department of hepatic biliary surgery, first affiliated hospital An Hui Medical University, HeFei 230022, AnHui Province, China

Gui-Hua Cheng, Jie-Fu Huang, Organ transplantation center, first affiliated hospital, Sun Yat-Sen University of Medical Sciences, GuangZhou 510089 GuangDong Province China

Author contributions: All authors contributed equally to the work.

Supported by clinic major project foundation of minister of health,No. 97040230

Correspondence to: Dr Ye-Ben Qian, Department of hepatic biliary surgery, first affiliated hospital An Hui Medical University, HeFei 230022, AnHui Province, China. ayqianyb@163.net

Telephone: +86-551-5129029

Received: May 30, 2001
Revised: September 23, 2001
Accepted: October 26, 2001
Published online: February 15, 2002

Abstract

AIM: To identify the risk factors relating to early mortality after orthotopic liver transplantation.

METHODS: Clinical data of 37 adult patients undergoing liver transplantation were retrospectively collected and divided into two groups: the survived group (survival time ≥ 30 d) and the death group (survival time < 30 d). The relationship between multivariate risk factors and early mortality after orthotopic liver transplantation were analyzed by stepwise logistic regression.

RESULTS: The survival rate was 73%. Early mortality rate was 27%. APACAE III, preoperative serum creatinine level and interoperative bleeding quantity had a significant independent association with early mortality. (R = 0.1841, 0.2056 and 0.3738).

CONCLUSION: APACHE III,preoperative serum creatinine level and interoperative bleeding quantity are significant risk factors relating to early mortality after orthotopic liver transplantation. To improve the recipient’s preoperative critical condition and renal function and to reduce interoperative bleeding quantity could lower the early mortality after orthotopic liver transplantation.

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