Original Articles
Copyright ©The Author(s) 1998. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 15, 1998; 4(4): 343-347
Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.343
Role and pitfalls of hepatic helical multi-phase CT scanning in differential diagnosis of small hemangioma and small hepatocellular carcinoma
Fu-Hua Yan, Meng-Su Zeng, Kang-Rong Zhou
Fu-Hua Yan, Meng-Su Zeng, Kang-Rong Zhou, Department of Radiology, Zhongshan Hospital, Shanghai Medical University, Shanghai 200032, China
Fu-Hua Yan, female, born on 1996-10-09 in Shanghai, graduated from Shanghai Medical University as a postgraduate in 1996, a radiologist in chief majoring the diagnosis of CT and MRI in hepatic diseases, having 11 papers published.
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Fu-Hua Yan, Department of Radiology, Zhongshan Hospital, Yi Xue Yuan Road, Shanghai 200032, China. krzhou@shmu.edu.cn
Telephone: +86-21-64041990 ext 2463
Received: January 31, 1998
Revised: March 18, 1998
Accepted: April 16, 1998
Published online: August 15, 1998
Abstract

AIM: To compare and analyze the contrast enhancement appearance of small hemangioma (SHHE) and small hepatocellular carcinoma (SHCC) with helical multi-phase CT scanning so as to determine their roles and pitfalls in the differential diagnosis of SHHE and SHCC.

METHODS: The pre and postcontrast CT scanning of the liver in 73 cases (38 SHHE, 35 SHCC) were carried out. The first phase scan of the entire liver began at 30s after the injection of contrast medium, the second and third phases began at 70s, and 4 min respectively. The contrast enhancement patterns and characteristics of all lesions were observed and compared.

RESULTS: In SHHE, 64.29% (27/42) had typical manifestations in two-phase dynamic scanning, such as peripheral dramatic high-density enhancement of the lesions with progressive opacification from the periphery toward the center, 30.95% (13/42) were hyperdense in both phases and 4.76% (2/42) were hypodense in both phases. In the third phase scanning, 96.67% (28/30) of SHHE were hyperdense and isodense. In SHCC 59.52% (25/42) presented typical appearances, such as hyperdense in the first phase and hypodense in the second phase, 23.81% (10/42) were hyperdense in the first phase and isodense in the second phase with 4.76% (2/42) of hypodense in both phases. In the third phase scanning, 85.71% (24/28) of SHCC were hypodense.

CONCLUSION: According to the contrast enhancement patterns of SHHE and SHCC in the two-phase or multi-phase scanning by helical CT, diagnosis can be established in the majority of lesions, while some atypical cases needed MRI for further investigation.

Keywords: liver neoplasms/radiography, carcinoma, hepatocellular/radiography, hemangioma/radiography, diagnosis, differential, tomography, X-ray computed