Original Articles
Copyright ©The Author(s) 1998. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 15, 1998; 4(4): 326-328
Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.326
Orientated thermotherapy of ferromagnetic thermoseed in hepatic tumors
Ren-Li Zhang, Yan Hu, Yun Ma, Xiang-Xiang Wang, Yue-Chun Geng
Yue-Chun Geng, Xiang-Xiang Wang, Yun Ma, Yan Hu, Xuzhou Institute of Medical Sciences, Xuzhou 221006, Jiangsu Province, China
Ren-Li Zhang, Department of Pathology, Xuzhou Medical Collage, Xuzhou 221006, Jiangsu Province, China
Yue-Chun Geng, male born on 1958-04-25 in Xuzhou City, Jiangsu Province, graduated from Nanjing Medical University in 1986, now a lecturer of biomagnetism, majoring medical biomagnetism, having 9 papers published.
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Yue-Chun Geng, Xuzhou Istitute of Medical Sciences, Hubei Road, Xuzhou 221006, Jiangsu Province, China
Telephone: +86-516-5797097
Received: March 8, 1998
Revised: April 24, 1998
Accepted: May 12, 1998
Published online: August 15, 1998
Abstract

AIM: To study the thermotherapeutic effects of implanted ferromagnetic thermoseeds in high frequency electromagnetic field in hepatic tumors.

METHODS: The ferromagnetic thermoseeds made of nickel-copper alloy, which has a lower Curie temperature, were implanted into hepatic tumors of mice. The high frequency electromagnetic field was then applied in vitro to make the ferromagnetic thermoseeds produce the hyperthermia. Before and after thermotherapy, the tumor size, pathologic alteration and animal survival period were assessed.

RESULTS: The temperature at the central area of the tumor could be heated up to 50 °C. Most of tumors in mice disappeared with a large amount of tumor necrosis. The survival period of mice was prolonged.

CONCLUSION: This thermotherapy is beneficial to directional selection and temperature control for treatment of hepatic tumors.

Keywords: liver neoplasms/therapy; eletromagnetic field; thermotherapy; liver neoplasms/pathology