Wu D, Song QY, Dai BS, Li J, Wang XX, Liu JY, Xie TY. Colorectal cancer early screening: Dilemmas and solutions. World J Gastroenterol 2025; 31(9): 98760 [DOI: 10.3748/wjg.v31.i9.98760]
Corresponding Author of This Article
Tian-Yu Xie, MD, PhD, Doctor, Surgeon, Surgical Oncologist, Department of General Surgery, First Medical Centre of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. xty930214@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Mar 7, 2025; 31(9): 98760 Published online Mar 7, 2025. doi: 10.3748/wjg.v31.i9.98760
Colorectal cancer early screening: Dilemmas and solutions
Di Wu, Qi-Ying Song, Bai-Shu Dai, Jie Li, Xin-Xin Wang, Jia-Yu Liu, Tian-Yu Xie
Di Wu, Qi-Ying Song, Bai-Shu Dai, Jie Li, Xin-Xin Wang, Tian-Yu Xie, Department of General Surgery, First Medical Centre of Chinese PLA General Hospital, Beijing 100853, China
Jia-Yu Liu, Department of Neurosurgery, First Medical Centre of Chinese PLA General Hospital, Beijing 100853, China
Co-first authors: Di Wu and Qi-Ying Song.
Co-corresponding authors: Jia-Yu Liu and Tian-Yu Xie.
Author contributions: Wu D, Liu JY and Xie TY conceived and designed the topic of the article; Song QY, Li J and Dai BS collected relative data and materials; Wu D and Song QY contributed to drafting and revising this article; Wang XX, Liu JY, Xie TY contributed to critical revision of the article for important intellectual content and final approval of the article.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tian-Yu Xie, MD, PhD, Doctor, Surgeon, Surgical Oncologist, Department of General Surgery, First Medical Centre of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. xty930214@163.com
Received: July 4, 2024 Revised: January 3, 2025 Accepted: January 13, 2025 Published online: March 7, 2025 Processing time: 228 Days and 9.7 Hours
Abstract
Colorectal cancer (CRC) is a prevalent malignancy worldwide, posing a significant public health concern. Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC, thereby enhancing patient prognosis. Obviously, non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients. In this letter, we provide a comprehensive overview of the current status of early screening practices, while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC. In response to these issues, we proffer a set of recommendations directed at governmental authorities and the general public, which focus on augmenting financial investment, establishing standardized screening protocols, advancing technological capabilities, and bolstering public awareness campaigns. The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC.
Core Tip: Pérez-Holanda et al identified that non-participation of asymptomatic candidates in screening protocols reduced early diagnosis and compromised long-term outcomes of colorectal cancer. We focus on the topic of dilemmas and solutions of early screening for colorectal cancer and profile the current landscape of early screening, propose recommendations for governments and the public.
