Luong TV, Le LD, Nguyen NVD, Dang HNN. Persistent challenges in the diagnosis of acute pancreatitis due to primary hyperparathyroidism during pregnancy. World J Gastroenterol 2025; 31(7): 100973 [DOI: 10.3748/wjg.v31.i7.100973]
Corresponding Author of This Article
Hai Nguyen Ngoc Dang, MD, Faculty of Medicine, Duy Tan University, No. 254 Nguyen Van Linh, Da Nang 550000, Viet Nam. ngochai123dc@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Feb 21, 2025; 31(7): 100973 Published online Feb 21, 2025. doi: 10.3748/wjg.v31.i7.100973
Persistent challenges in the diagnosis of acute pancreatitis due to primary hyperparathyroidism during pregnancy
Thang Viet Luong, Linh Duy Le, Nam Van Duc Nguyen, Hai Nguyen Ngoc Dang
Thang Viet Luong, Linh Duy Le, Nam Van Duc Nguyen, Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Hue 530000, Viet Nam
Hai Nguyen Ngoc Dang, Faculty of Medicine, Duy Tan University, Da Nang 550000, Viet Nam
Co-first authors: Thang Viet Luong and Linh Duy Le.
Author contributions: Luong TV, Le LD, and Nguyen NVD contributed to the conceptualization of the study and drafted the original manuscript; Dang HNN was responsible for designing the figures; and all authors were actively involved in writing, reviewing, editing, and drafting of the manuscript and read and approved its final version; Luong TV managed the entire research process and Le LD oversaw and refined the content of the manuscript, they contributed equally as co-first authors.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai Nguyen Ngoc Dang, MD, Faculty of Medicine, Duy Tan University, No. 254 Nguyen Van Linh, Da Nang 550000, Viet Nam. ngochai123dc@gmail.com
Received: September 5, 2024 Revised: December 1, 2024 Accepted: January 2, 2025 Published online: February 21, 2025 Processing time: 136 Days and 23.8 Hours
Abstract
In this manuscript, we provide critical commentary on the systematic review by Augustin et al, which investigated acute pancreatitis induced by primary hyperparathyroidism during pregnancy. Although this is an infrequent complication, it poses severe risks to both maternal and fetal health. Due to its infrequent occurrence in clinical practice, this review is based on an analysis of individual case reports over the past 55 years. While this is not the first study to utilize this sampling method for primary hyperparathyroidism-induced acute pancreatitis, it is unique in that it has a sufficiently large sample size with statistically significant results. Our discussion focuses on the diagnostic challenges associated with this condition, which are grounded in the mechanisms of parathyroid hormone secretion and variations in serum calcium levels. We also address the limitations of the current review and suggest potential strategies to increase diagnostic accuracy and improve health outcomes for both mothers and fetuses during pregnancy.
Core Tip: This manuscript focuses on a systematic review of acute pancreatitis triggered by primary hyperparathyroidism during pregnancy, with an emphasis on diagnostic challenges. The study explored the mechanisms of parathyroid hormone secretion and serum calcium variations during pregnancy and analyzed their effects on maternal and fetal health. Additionally, this article highlights current research limitations and offers potential solutions and future research directions to improve diagnostic methods and enhance healthcare outcomes for both mothers and fetuses.
