Application of ultrasound elastography and splenic size in predicting post-hepatectomy liver failure: Unveiling new clinical perspectives

Abstract

In this article, we discuss the study by Cheng et al, published in the World Journal of Gastroenterology, focusing on predictive methods for post-hepatectomy liver failure (PHLF). PHLF is a common and serious complication, and accurate prediction is critical for clinical management. The study examines the potential of ultrasound elastography and splenic size in predicting PHLF. Ultrasound elastography reflects liver functional reserve, while splenic size provides additional predictive value. By integrating these factors with serological markers, we developed a comprehensive prediction model that effectively stratifies patient risk and supports personalized clinical decisions. This approach offers new insights into predicting PHLF. These methods not only assist clinicians in identifying high-risk patients earlier but also provide scientific support for personalized treatment strategies. Future research will aim to validate the model's accuracy with larger sample sizes, further enhancing the clinical application of these non-invasive indicators.

Keywords: Ultrasound elastography; Splenic size; Post-hepatectomy liver failure; Prediction model; Risk stratification

Core Tip: This article discusses a study on predictive methods for post-hepatectomy liver failure (PHLF), highlighting the potential of ultrasound elastography and splenic size in predicting PHLF, as these factors reflect liver function and portal hemodynamics. By combining these variables with serological markers, a comprehensive prediction model was developed to aid in risk stratification and inform personalized clinical decisions. This approach offers new insights into the early identification of high-risk patients and supports personalized treatment strategies. Future research will validate the model’s accuracy using with larger sample sizes for broader clinical application.