Jiang ZX, Yuan LW, Peng LX, Yang LC, Zhang YW, Wu Q, Yao BJ, Wang XH. Idiopathic myointimal hyperplasia of the mesenteric veins affecting the small intestine alone: A case report and review of literature. World J Gastroenterol 2025; 31(18): 103778 [DOI: 10.3748/wjg.v31.i18.103778]
Corresponding Author of This Article
Lian-Wen Yuan, PhD, Chief Physician, Professor, Department of General Surgery, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. yuanlianwen@csu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Zhi-Xian Jiang, Lian-Wen Yuan, Liang-Xin Peng, Li-Chao Yang, Ya-Wei Zhang, Qiang Wu, Bao-Jia Yao, Department of General Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Xue-Hong Wang, Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Author contributions: Jiang ZX contributed to the manuscript writing, editing, and data collection; Peng LX contributed to the manuscript writing; Zhang YW, Yang LC, Wu Q, Yao BJ, and Wang XH contributed to the revision of the manuscript; Yuan LW contributed to the revision of the manuscript and supervision of the project; All of the authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 81970493 and No. 82270590.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lian-Wen Yuan, PhD, Chief Physician, Professor, Department of General Surgery, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. yuanlianwen@csu.edu.cn
Received: December 2, 2024 Revised: February 26, 2025 Accepted: April 16, 2025 Published online: May 14, 2025 Processing time: 163 Days and 5 Hours
Abstract
BACKGROUND
Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare disease characterized by narrowing of the lumen caused by mesenteric vein intimal hyperplasia, resulting in chronic intestinal ischemia. Although the colorectum is the primary site affected by this condition, involvement of the small intestine is even more rare. Recurrence of IMHMV after surgical resection of the affected bowel is uncommon.
CASE SUMMARY
In this case report, we present a unique instance of IMHMV exclusively occurring in the small intestine. The patient experienced small intestinal perforation, infarction, and obstruction before receiving a clear diagnosis, which was achieved only during the third operation. In this review, we analyzed 84 reported cases to summarize the etiology, clinical manifestations, and diagnostic challenges of IMHMV, with the aim of raising awareness regarding this rare condition among clinicians.
CONCLUSION
Notably, IMHMV can also affect the small intestine alone. When refractory enteritis with endoscopic findings of nonspecific ischemic changes is encountered, IMHMV should be considered for potential diagnosis.
Core Tip: Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare vascular disorder that typically affects the colorectum but can also involve the small intestine. We present a unique case of IMHMV exclusively affecting the small intestine, in which the patient experienced small intestinal perforation, infarction, and obstruction before a definitive diagnosis was made. This report emphasizes the importance of early recognition and highlights the diagnostic challenges faced by patients. A review of 84 cases helps increase awareness and understanding of the clinical presentation, diagnosis, and management of IMHMV.
