Zhang C, Ouyang YW, Li ZT. Role of Helicobacter pylori in esophageal carcinogenesis: Friend or foe? World J Gastroenterol 2024; 30(44): 4759-4762 [DOI: 10.3748/wjg.v30.i44.4759]
Corresponding Author of This Article
Cong Zhang, MD, PhD, Doctor, Department of Gastroenterology, The First People’s Hospital of Foshan, No. 81 Lingnan Avenue North, Foshan 528000, Guangdong Province, China. zhangc57@mail2.sysu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 28, 2024; 30(44): 4759-4762 Published online Nov 28, 2024. doi: 10.3748/wjg.v30.i44.4759
Role of Helicobacter pylori in esophageal carcinogenesis: Friend or foe?
Cong Zhang, Yong-Wen Ouyang, Zhao-Tao Li
Cong Zhang, Yong-Wen Ouyang, Zhao-Tao Li, Department of Gastroenterology, The First People’s Hospital of Foshan, Foshan 528000, Guangdong Province, China
Co-first authors: Cong Zhang and Yong-Wen Ouyang.
Co-corresponding authors: Cong Zhang and Zhao-Tao Li.
Author contributions: Zhang C and Ouyang YW designed the manuscript outline and contributed to writing the manuscript; Zhang C and Li ZT designed the overall concept of the manuscript and revised the draft; All the authors have read and approved the final manuscript.
Supported bythe Guangdong Basic and Applied Basic Research Foundation, No. 2023A1515140118.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cong Zhang, MD, PhD, Doctor, Department of Gastroenterology, The First People’s Hospital of Foshan, No. 81 Lingnan Avenue North, Foshan 528000, Guangdong Province, China. zhangc57@mail2.sysu.edu.cn
Received: August 10, 2024 Revised: September 22, 2024 Accepted: October 22, 2024 Published online: November 28, 2024 Processing time: 93 Days and 17.6 Hours
Abstract
In this letter, we comment on the article by López-Gómez et al, which explores the prevalence of Helicobacter pylori (H. pylori) infection among patients with esophageal carcinoma (EC) in a cohort of Spain population. The relationship between H. pylori infection and EC is very complex. Previous research results are often contradictory due to the influence of dietary habits, age, region, and other factors. López-Gómez et al reported a very low prevalence of previous H. pylori infection in their cohort of patients with EC, and most of them had previously received or concomitantly received proton pump inhibitors treatment. These results are similar to previous results, which suggest that H. pylori infection is related to the low incidence of EC. Therefore, this study may provide a direction for preventing EC and eradicating H. pylori in Spain.
Core Tip: López-Gómez et al provided evidence of a very low prevalence of previous Helicobacter pylori infection in a Spanish cohort of patients with esophageal carcinoma, and most of those patients had previously received or concomitantly received proton pump inhibitors treatment. However, more studies (such as prospective studies or Mendelian randomization studies) are still needed to confirm the causal relationship between them in the future.
