Feng YN, Liu LH, Zhang HW. Evaluation of the GATIS score for predicting prognosis in rectal neuroendocrine neoplasms. World J Gastroenterol 2024; 30(42): 4587-4590 [PMID: 39563742 DOI: 10.3748/wjg.v30.i42.4587]
Corresponding Author of This Article
Han-Wen Zhang, MD, PhD, Doctor, Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People’s Hospital, No. 3002 Sungangxi Road, Shenzhen 518000, Guangdong Province, China. zhwstarcraft@outlook.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 14, 2024; 30(42): 4587-4590 Published online Nov 14, 2024. doi: 10.3748/wjg.v30.i42.4587
Evaluation of the GATIS score for predicting prognosis in rectal neuroendocrine neoplasms
Yu-Ning Feng, Li-Hong Liu, Han-Wen Zhang
Yu-Ning Feng, Li-Hong Liu, Han-Wen Zhang, Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People’s Hospital, Shenzhen 518000, Guangdong Province, China
Co-first authors: Yu-Ning Feng and Li-Hong Liu.
Author contributions: Feng YN and Liu LH contribute equally to this study as co-first authors. Feng YN and Liu LH wrote an analytical article to comment on the study; Zhang HW revised and reviewed the article.
Supported byGuangdong Medical Science and Technology Research Fund Project, No. A2024475.
Conflict-of-interest statement: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Han-Wen Zhang, MD, PhD, Doctor, Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People’s Hospital, No. 3002 Sungangxi Road, Shenzhen 518000, Guangdong Province, China. zhwstarcraft@outlook.com
Received: July 24, 2024 Revised: September 16, 2024 Accepted: October 14, 2024 Published online: November 14, 2024 Processing time: 98 Days and 21 Hours
Abstract
The GATIS score, developed by Zeng et al, represents a significant advancement in predicting the prognosis of patients with rectal neuroendocrine neoplasms (R-NENs). This study, which included 1408 patients from 17 major medical centres in China over 12 years, introduces a novel prognostic model based on the tumour grade, T stage, tumour size, age, and the prognostic nutritional index. Compared with traditional methods such as the World Health Organization classification and TNM staging systems, the GATIS score has superior predictive power for overall survival and progression-free survival. With a C-index of 0.915 in the training set and 0.812 in the external validation set, the GATIS score’s robustness and reliability are evident. The study’s use of a large, multi-centre cohort and rigorous validation processes underscore its significance. The GATIS score offers clinicians a powerful tool to accurately predict patient outcomes, guide treatment decisions, and improve follow-up strategies. This development represents a crucial step forwards in the management of R-NENs, addressing the complexity and variability of these tumours and setting a new benchmark for future research and clinical practice.
Core Tip: Compared with traditional methods, the GATIS score is a novel, highly accurate prognostic tool for rectal neuroendocrine neoplasms, offering superior predictive power for overall and progression-free survival.
