Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 14, 2024; 30(42): 4566-4568
Published online Nov 14, 2024. doi: 10.3748/wjg.v30.i42.4566
Colon cancer screening programs prevent cancer
Duncan J Flynn, Joseph D Feuerstein
Duncan J Flynn, Joseph D Feuerstein, Department of Medicine and Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United States
Co-first authors: Duncan J Flynn and Joseph D Feuerstein.
Author contributions: Flynn DJ and Feuerstein JD contributed to manuscript development.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Joseph D Feuerstein, AGAF, MD, Associate Professor, Attending Doctor, Department of Medicine and Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St 8E, Boston, MA 02215, United States. jfeuerst@bidmc.harvard.edu
Received: April 28, 2024
Revised: September 9, 2024
Accepted: October 15, 2024
Published online: November 14, 2024
Processing time: 186 Days and 4 Hours
Abstract

In this article we comment on the article by Agatsuma et al. Our article focuses on the use of screening for colon cancer increases the likelihood of early diagnosis of colorectal cancer compared to those presenting after symptoms develop. Patients with symptoms were more likely to have left-sided lesions with resultant hematochezia and/or changes in bowel habits. In this study almost all patients in the screen group were first screened with immunochemical fecal occult blood testing. Colonoscopy was used either if it was thought to be the more appropriate initial screening modality or if the non-invasive test was positive. The exact timing when an initial screening colonoscopy should be performed is not totally clear from this study. However, early screening for colon cancer does reduce the risk of cancer diagnosis and more advanced cancer diagnoses.

Keywords: Colon cancer; Screening; Colonoscopy; Quality; Prevention

Core Tip: Colon cancer is rising in incidence and prevalence worldwide. Colon cancer screening programs are associated with reduction in cancer diagnoses and in advanced stages of cancer diagnoses. The ideal screening test remains unclear but both fecal immunochemical test (FIT) testing and colonoscopy are both appropriate modalities. Ultimately, if a patient has risk factors or if the FIT test is positive, then colonoscopy should be used to evaluate for colon cancer.