Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2024; 30(33): 3818-3822
Published online Sep 7, 2024. doi: 10.3748/wjg.v30.i33.3818
Early diagnostic strategies for colorectal cancer
Shi-Cai Liu, Han Zhang
Shi-Cai Liu, School of Medical Information, Wannan Medical College, Wuhu 241002, Anhui Province, China
Han Zhang, School of Basic Medical Sciences, Wannan Medical College, Wuhu 241002, Anhui Province, China
Author contributions: Liu SC designed the overall concept and outline of the manuscript, contributed to the discussion and design of the manuscript; Liu SC and Zhang H contributed to the writing and editing of the manuscript, illustrations, and review of the literature; All authors approved the final version of the manuscript.
Supported by the Talent Scientific Research Start-up Foundation of Wannan Medical College, No. WYRCQD2023045.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shi-Cai Liu, PhD, Academic Research, School of Medical Information, Wannan Medical College, No. 22 Wenchang West Road, Wuhu 241002, Anhui Province, China. liushicainj@163.com
Received: July 15, 2024
Revised: August 9, 2024
Accepted: August 19, 2024
Published online: September 7, 2024
Processing time: 48 Days and 22.9 Hours
Abstract

At present, cancer is still an important factor threatening human health. Colorectal cancer (CRC) is one of the top three most common cancers worldwide and one of the deadliest malignancies in humans. The latest data showed that CRC incidence and mortality rank third and second, respectively, among global malignancies. Early and accurate diagnosis is crucial to reduce the morbidity, mortality and improve survival of patients with CRC, but the current early diagnostic methods have limitations. The effectiveness and compliance of diagnostic methods have a certain impact on whether people choose screening. In this editorial, we explore strategies for the early diagnosis of CRC, including stool-based, blood-based, direct visualization, and imaging examinations.

Keywords: Colorectal cancer; Diagnostic markers; Colonoscopy; Fecal immunochemical test; Fecal occult blood test; Circulating tumor cells; Circulating tumor DNA

Core Tip: Colorectal cancer is one of the top three most common cancers worldwide, with high morbidity and mortality. Early and accurate diagnosis is crucial, but the existing diagnostic methods are limited. Stool-based, blood-based, direct visualization and imaging examinations are the current early diagnosis strategies, which should be promoted and improved to decrease morbidity and mortality of patients and improve their prognosis and survival.