Scientometrics
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2024; 30(30): 3609-3624
Published online Aug 14, 2024. doi: 10.3748/wjg.v30.i30.3609
Bibliometric study of sepsis-associated liver injury from 2000 to 2023
Zheng Zhang, Xiao-Jiao Tan, Hai-Qing Shi, Huan Zhang, Jian-Bo Li, Xue-Lian Liao
Zheng Zhang, Xiao-Jiao Tan, Hai-Qing Shi, Huan Zhang, Jian-Bo Li, Xue-Lian Liao, Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Xue-Lian Liao, Department of Critical Care Medicine, West China Tianfu Hospital of Sichuan University, Chengdu 610200, Sichuan Province, China
Author contributions: Zhang Z and Tan XJ contributed to conceptualization and investigation; Tan XJ and Shi HQ contributed to data curation; Zhang Z and Li JB contributed to formal analysis, methodology, visualization and writing - original draft; Liao XL contributed to funding acquisition, project administration, and supervision; Tan XJ, Shi HQ and Zhang H contributed to resources, and validation; Zhang Z contributed to software; Tan XJ, Shi HQ, Zhang H, Liao XL contributed to writing - review & editing; All authors have read and approved the final manuscript.
Supported by National Key R & D Program Projects, No. 2022YFC2009804.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xue-Lian Liao, MD, Doctor, Department of Critical Care Medicine, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan Province, China. liaoxuelian@scu.edu.cn
Received: March 13, 2024
Revised: June 28, 2024
Accepted: July 16, 2024
Published online: August 14, 2024
Processing time: 149 Days and 9.1 Hours
Abstract
BACKGROUND

Sepsis-associated liver injury (SLI) is a severe and prevalent complication of sepsis.

AIM

To explore the literature on SLI via a bibliometric approach.

METHODS

Reviews and articles correlated with SLI published from January 1, 2000 to October 28, 2023 were searched from the Web of Science Core Collection. Then, the searched data were analyzed using VOSviewer, CiteSpace, and R language.

RESULTS

There were 787 publications involved in this paper, comprising 745 articles and 42 reviews. China, the United States, and Germany are the primary publication sources in this area. Studies related to SLI primarily focused on mechanisms of pathogenesis, as evidenced by analyzing keywords, references, and the counting of original research. These studies mainly involved tumor necrosis factor alpha, inflammation, oxidative stress, and nuclear factor-kappa B.

CONCLUSION

There is significant growth in the research on SLI. Current investigations primarily involve basic experiments that aimed at uncovering pathogenic mechanisms. According to the analyzed literature, the identified pathogenic mechanisms and potential therapeutic targets serve as the foundation for translating findings from basic research to clinical applications.

Keywords: Sepsis, Liver injury, Bibliometric analysis, Cite space, VOS viewer

Core Tip: NLRP3 inflammasome is the most recent keyword exhibiting the most significant citation bursts. The revelation of pathogenic mechanisms and potential therapeutic targets serves as the basis for translating from basic research to clinical application. In conclusion, our research will offer a helpful reference for subsequent studies on sepsis-associated liver injury.