Pan Y, Jiao FY. Link between childhood obesity and gut microbiota. World J Gastroenterol 2024; 30(30): 3560-3563 [DOI: 10.3748/wjg.v30.i30.3560]
Corresponding Author of This Article
Fu-Yong Jiao, PhD, Senior Scientist, Shaanxi Kawasaki Disease Diagnosis and Treatment Center, Children's Hospital, Shaanxi Provincial People's Hospital of Xi'an, Jiaotong University, No. 256 Youyi West Road, Beilin District, Xi'an 710000, Shaanxi Province, China. 3105089948@qq.com
Research Domain of This Article
Microbiology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Aug 14, 2024; 30(30): 3560-3563 Published online Aug 14, 2024. doi: 10.3748/wjg.v30.i30.3560
Link between childhood obesity and gut microbiota
Yan Pan, Fu-Yong Jiao
Yan Pan, Department of Pediatrics, The First Affiliated Hospital of Yangtze University, Jingzho 434000, Hubei Province, China
Fu-Yong Jiao, Shaanxi Kawasaki Disease Diagnosis and Treatment Center, Children's Hospital, Shaanxi Provincial People's Hospital of Xi'an, Jiaotong University, Xi'an 710000, Shaanxi Province, China
Author contributions: Jiao FY designed the research study; Pan Y designed the research study, performed the research, contributed new reagents and analytic tools, analyzed the data, wrote the manuscript, read and approve the final manuscript.
Supported byThe Hubei Pediatric Alliance Medical Research Project, No. HPAMRP202117.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fu-Yong Jiao, PhD, Senior Scientist, Shaanxi Kawasaki Disease Diagnosis and Treatment Center, Children's Hospital, Shaanxi Provincial People's Hospital of Xi'an, Jiaotong University, No. 256 Youyi West Road, Beilin District, Xi'an 710000, Shaanxi Province, China. 3105089948@qq.com
Received: June 27, 2024 Revised: July 18, 2024 Accepted: July 26, 2024 Published online: August 14, 2024 Processing time: 42 Days and 23.4 Hours
Abstract
Childhood obesity is a critical global health concern with rising prevalence and significant long-term health implications. Recent studies have implicated gut microbiota in the development and progression of obesity. This editorial analyzes the research conducted by Li et al, who utilized 16S rRNA gene sequencing to compare the gut microbiome of overweight and healthy-weight children. The study found significant differences in microbial diversity and composition between the two groups, with potential implications for understanding and managing childhood obesity. We analyzed the study’s advantages and drawbacks, proposing potential areas for future research to better understand the connection between gut microbiota and obesity.
Core Tip: Childhood obesity is a growing health concern worldwide, with new studies emphasizing the impact of gut bacteria on its onset and advancement. The study by Li et al employed 16S rRNA gene sequencing to analyze the gut microbiome of overweight and healthy children, uncovering notable variations in microbial richness and structure among the two cohorts. Obese children exhibited an increased abundance of Prevotella and Firmicutes and decreased presence of Bacteroides and Sanguibacteroides, underscoring the significance of environmental and lifestyle factors in future research and interventions. Exploring the connection between gut bacteria and obesity can aid in devising specific prevention and treatment approaches, such as customized dietary plans and therapies based on microbiota, to enhance the metabolic well-being of kids.
