Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2024; 30(29): 3456-3460
Published online Aug 7, 2024. doi: 10.3748/wjg.v30.i29.3456
Effective roles of exercise and diet adherence in non-alcoholic fatty liver disease
Wei Zhu
Wei Zhu, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China
Wei Zhu, Shanghai Xirong Information Science and Technology Co., Ltd., National Science and Technology Park, Tongji University, Shanghai 200092, China
Author contributions: Zhu W designed the study, wrote the manuscript, and prepared the figure and table, in addition to other associated work.
Supported by Natural Science Foundation of Shanghai, No. 17ZR1431400; and National Key R&D Program of China, No. 2017YFA0103902.
Conflict-of-interest statement: The authors have no competing interests related to this study.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Zhu, PhD, CEO, Postdoctoral Fellow, Researcher, School of Life Sciences and Technology, Tongji University, No. 1239 Siping Road, Yangpu District, Shanghai 200092, China. zhuwei8247@aliyun.com
Received: March 7, 2024
Revised: June 22, 2024
Accepted: July 1, 2024
Published online: August 7, 2024
Processing time: 143 Days and 15.8 Hours
Abstract

Non-alcoholic fatty liver disease (NAFLD) is characterized by symptoms of excessive fat accumulation and steatosis in the liver without alcohol intake in patients. The associated pathogenic mechanism is not completely understood and there are no specific drugs for patients with NAFLD. Exercise and diet adherence are the best options for the management of NAFLD patients. Questionnaire associated analysis models of adherence to these interventions are used to assess their effectiveness in the management of NAFLD patients using specificity, sensitivity, and so on. Studies have indicated that the relative ratio of NAFLD can be reduced by physical activity with diet control. In the future, the pathogenesis of NAFLD should be clarified with stratified efforts to develop appropriate drugs, and both exercise and diet adherence should be optimized using better questionnaire design and evaluation models for patients with NAFLD.

Keywords: Exercise and diet adherence, Non-alcoholic fatty liver disease, Delphi, Mediterranean diet, Physical lifestyle

Core Tip: It is essential to reverse pathogenic syndromes before fibrosis occurs in patients with non-alcoholic fatty liver disease (NAFLD). Early diagnosis and appropriate interventions are important in NAFLD patients. Exercise and diet adherence may provide an effective treatment in patients with NAFLD.