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World J Gastroenterol. Jul 28, 2024; 30(28): 3386-3392
Published online Jul 28, 2024. doi: 10.3748/wjg.v30.i28.3386
Is appendoscope a new option for the treatment of acute appendicitis?
Shu-Jiong Feng, Yi-Feng Zhou, Jian-Feng Yang, Hong-Zhang Shen, Guang-Xing Cui, Xiao-Feng Zhang
Shu-Jiong Feng, Yi-Feng Zhou, Jian-Feng Yang, Hong-Zhang Shen, Guang-Xing Cui, Xiao-Feng Zhang, Department of Gastroenterology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China
Shu-Jiong Feng, Yi-Feng Zhou, Jian-Feng Yang, Hong-Zhang Shen, Guang-Xing Cui, Xiao-Feng Zhang, Department of Gastroenterology, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Biliary and Pancreatic Diseases of Zhejiang Province, Hangzhou 310000, Zhejiang Province, China
Shu-Jiong Feng, Yi-Feng Zhou, Jian-Feng Yang, Hong-Zhang Shen, Guang-Xing Cui, Xiao-Feng Zhang, Department of Gastroenterology, Hangzhou Institute of Digestive Diseases, Hangzhou 310000, Zhejiang Province, China
Author contributions: Feng SJ was responsible for writing the main content of the article; Zhou YF performed appendoscope; Yang JF searched the literature and performed endoscopic retrograde appendicitis therapy; Shen HZ edited figures; Cui GX polished language and performed endoscopic retrograde appendicitis therapy; Zhang XF was mainly responsible for revising the content of the article; and all authors have read and approved the final manuscript.
Supported by the Construction Fund of Key Medical Disciplines of Hangzhou, No. 0020200026; and Key R&D Program of Zhejiang Province, No. 2023C03054.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Feng Zhang, MD, Chief Physician, Department of Gastroenterology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Hangzhou 310000, Zhejiang Province, China. zxf837@tom.com
Received: April 7, 2024
Revised: June 11, 2024
Accepted: July 1, 2024
Published online: July 28, 2024
Processing time: 107 Days and 17 Hours
Abstract

Acute appendicitis is a common surgical emergency. It is commonly caused by obstruction of the appendiceal lumen due to fecaliths, tumors, or lymphoid hyperplasia. For over a century, appendectomy has been the primary treatment for acute appendicitis. Abraham Groves performed the first open appendectomy in 1883. In 1983, Kurt Semm completed the first laparoscopic appendectomy, heralding a new era in appendectomy. However, appendectomy is associated with certain complications and a rate of negative appendectomies. Studies have suggested controversy over the impact of appendectomy on the development of inflammatory bowel disease and Parkinson’s disease, but an increasing number of studies indicate a possible positive correlation between appendectomy and colorectal cancer, gallstones, and cardiovascular disease. With the recognition that the appendix is not a vestigial organ and the advancement of endoscopic te-chnology, Liu proposed the endoscopic retrograde appendicitis therapy. It is an effective minimally invasive alternative for treating uncomplicated acute appendicitis. Our team has developed an appendoscope with a disposable digital imaging system operated through the biopsy channel of a colonoscope and successfully applied it in the treatment of appendicitis. This article provides an overview of the progress in endoscopic treatment for acute appendicitis and offers a new perspective on the future direction of appendiceal disease treatment.

Keywords: Acute appendicitis; Endoscopic technology; Endoscopic retrograde appendicitis therapy; Appendoscope; Appendiceal disease treatment

Core Tip: In this article, our team has developed an appendoscope with a disposable digital imaging system operated through the biopsy channel of a colonoscope and successfully applied it in the treatment of appendicitis. It provides an overview of the progress in endoscopic treatment for acute appendicitis and offers a new perspective on the future direction of appendiceal disease treatment.