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World J Gastroenterol. Mar 28, 2024; 30(12): 1706-1713
Published online Mar 28, 2024. doi: 10.3748/wjg.v30.i12.1706
Endoscopic treatment of scarred polyps with a non-thermal device (Endorotor): A review of the literature‎
Mariam Zaghloul, Hameed Rehman, Stefano Sansone, Konstantinos Argyriou, Adolfo Parra-Blanco
Mariam Zaghloul, Department of Hepatology, Gastroenterology and Infectious Diseases, Kafrelsheikh Universit, Kafr-Elshikh 33516, Egypt
Hameed Rehman, Stefano Sansone, Adolfo Parra-Blanco, Department of Gastroenterology Service, Nottingham City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham NG5 1PB, United Kingdom
Konstantinos Argyriou, Department of Gastroenterology, University Hospital of Larissa, Larissa 41334, Greece
Adolfo Parra-Blanco, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG72UH, United Kingdom
Author contributions: Zaghloul M and Parra-Blanco A designed the review; Zaghloul M reviewed the literature and wrote the manuscript; Parra-Blanco A, Sansone S, Rehman H and Argyriou K reviewed the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: Dr. Parra-Blanco reports other from Inter scope, during the conduct of the study; other from Lumendi and CREO medical, other from Puramatrix, outside the submitted work.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Adolfo Parra-Blanco, MD, PhD, FJGESNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, street number, Nottingham NG72UH, United Kingdom. adolfo.parra-blanco@nottingham.ac.uk
Received: November 26, 2023
Peer-review started: November 26, 2023
First decision: December 14, 2023
Revised: January 22, 2024
Accepted: March 15, 2024
Article in press: March 28, 2024
Published online: March 28, 2024
Processing time: 122 Days and 16.4 Hours
Abstract

Endoscopic resection (ER) of colorectal polyps has become a daily practice in most endoscopic units providing a colorectal cancer screening program and requires the availability of local experts and high-end endoscopic devices. ER procedures have evolved over the past few years from endoscopic mucosal resection (EMR) to more advanced techniques, such as endoscopic submucosal dissection and endo-scopic full-thickness resection. Complete resection and disease eradication are the ultimate goals of ER-based techniques, and novel devices have been developed to achieve these goals. The EndoRotor® Endoscopic Powered Resection System (Interscope Medical, Inc., Northbridge, Massachusetts, United States) is one such device. The EndoRotor is a powered resection tool for the removal of alimentary tract mucosa, including post-EMR persistent lesions with scarring, and has both CE Mark and FDA clearance. This review covers available published evidence documenting the usefulness of EndoRotor for the management of recurrent colorectal polyps.

Keywords: EndoRotor; Scarred polyps; Recurrent polyps; Colorectal cancer; Colorectal polyps

Core Tip: Colorectal cancer (CRC) screening was initiated and implemented over the last two decades with a widespread ‎variability in strategies and coverage in different parts of Europe even after the first appearance ‎of the European guidelines for CRC screening. Recurrent or previously manipulated lesions are usually fibrotic with tethering to the muscularis ‎and display the non-lifting sign, making subsequent resection challenging.‎ The EndoRotor® Endoscopic Powered Resection System is a powered debridement device for the removal of ‎alimentary tract mucosa, including post-endoscopic mucosal resection persistent lesions with scarring, and has both CE ‎Mark and FDA clearance. This review covers available published evidence documenting the ‎usefulness of EndoRotor for the management of recurrent scarred colorectal polyps.‎