Review
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 28, 2023; 29(40): 5526-5542
Published online Oct 28, 2023. doi: 10.3748/wjg.v29.i40.5526
Overview on the endoscopic treatment for obesity: A review
Maheeba Abdulla, Nafeesa Mohammed, Jehad AlQamish
Maheeba Abdulla, Jehad AlQamish, Department of Internal Medicine, Ibn Al Nafees Hospital, Manama 54533, Bahrain
Nafeesa Mohammed, Department of Intensive Care Unit, Salmaniya Medical Complex, Manama 5616, Bahrain
Author contributions: Abdulla M, Mohammed N, and AlQamish J contributed to the colleting the data, review, editing, and finalizing the manuscript; Abdulla M designed the review and wrote the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maheeba Abdulla, MD, MRCP, Consultant Physician, Gastroenterologist & Hepatologist, Department of Internal Medicine, Ibn Al Nafees Hospital, No. 3302 Road, Manama 54533, Bahrain. amaheeba@hotmail.com
Received: August 3, 2023
Peer-review started: August 3, 2023
First decision: September 5, 2023
Revised: September 15, 2023
Accepted: October 23, 2023
Article in press: October 23, 2023
Published online: October 28, 2023
Abstract

Obesity rates have increased, and so has the need for more specific treatments. This trend has raised interest in non-surgical weight loss techniques that are novel, safe, and straightforward. Thus, the present review describes the endoscopic bariatric treatment for obesity, its most recent supporting data, the questions it raises, and its future directions. Various endoscopic bariatric therapies for weight reduction, such as intragastric balloons (IGBs), aspiration therapy (AT), small bowel endoscopy, endoscopic sleeve gastroplasty, endoluminal procedures, malabsorption endoscopic procedures, and methods of regulating gastric emptying, were explored through literature sourced from different databases. IGBs, AT, and small bowel endoscopy have short-term effects with a possibility of weight regain. Minor adverse events have occurred; however, all procedures reduce weight. Vomiting and nausea are common side effects, although serious complications have also been observed.

Keywords: Overweight, Gastric bypass, Malabsorption, Intragastric balloons

Core Tip: To enhance endoscopic intervention effectiveness and patent satisfaction, the research recommends device design, procedures, patient selection, and personalized therapy. Endoscopists, bariatric surgeons, and researchers must collaborate to solve problems, improve patient comfort, and reduce treatment risks. Effective weight maintenance through endoscopic methods and patient education requires comprehensive and long-term follow-up. Robotic-assisted endoscopy and tissue-engineered implants may revolutionize obesity treatment and patient outcomes in five to ten years.