Charley E, Dinner B, Pham K, Vyas N. Diabetes as a consequence of acute pancreatitis. World J Gastroenterol 2023; 29(31): 4736-4743 [PMID: 37664150 DOI: 10.3748/wjg.v29.i31.4736]
Corresponding Author of This Article
Ericka Charley, MD, Gastroenterology Fellow Department of Gastroenterology, Creighton University - Phoenix, 350 W Thomas Road, Phoenix, AZ 85013, United States. erickaziggycharley@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Aug 21, 2023; 29(31): 4736-4743 Published online Aug 21, 2023. doi: 10.3748/wjg.v29.i31.4736
Diabetes as a consequence of acute pancreatitis
Ericka Charley, Brett Dinner, Kimberly Pham, Neil Vyas
Ericka Charley, Department of Gastroenterology, Creighton University - St. Joseph’s Hospital and Medical Center Phoenix, AZ 85013, United States
Brett Dinner, Kimberly Pham, Department of Internal Medicine, Creighton University St. Joseph’s Hospital and Medical Center, Phoenix, AZ 85013, United States
Neil Vyas, Department of Gastroenterology, Creighton University St. Joseph’s Hospital and Medical Center, Phoenix, AZ 85013, United States
Author contributions: Charley E contributed to the final review; Charley E and Dinner B composed the paper; Dinner B added to the literature review and created the included figure; Charley E and Pham K conducted the literature review; Pham K made critical revisions; Vyas N provided mentorship, contributed to the overall concept and made critical revisions; and all authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ericka Charley, MD, Gastroenterology Fellow Department of Gastroenterology, Creighton University - Phoenix, 350 W Thomas Road, Phoenix, AZ 85013, United States. erickaziggycharley@gmail.com
Received: June 26, 2023 Peer-review started: June 26, 2023 First decision: July 5, 2023 Revised: July 17, 2023 Accepted: July 28, 2023 Article in press: July 28, 2023 Published online: August 21, 2023 Processing time: 53 Days and 8.5 Hours
Abstract
Diabetes is a highly prevalent disease that was initially simplified into three major types: Type 1, type 2 and gestational diabetes. With the global rise in incidence of acute pancreatitis (AP), a lesser-known type of diabetes referred to as diabetes of the exocrine pancreas (DEP) is becoming more recognized. However, there is a poor understanding of the inherent relationship between diabetes and AP. There is established data about certain diseases affecting the exocrine function of the pancreas which can lead to diabetes. More specifically, there are well established guidelines for diagnosis and management of DEP caused be chronic pancreatitis. Conversely, the sequelae of AP leading to diabetes has limited recognition and data. The purpose of this review is to provide a comprehensive summary of the prevalence, epidemiology, pathophysiology and future research aims of AP-related diabetes. In addition, we propose a screening and diagnostic algorithm to aid clinicians in providing better care for their patients.
Core Tip: Acute pancreatitis (AP)-related diabetes has limited recognition and data. The disease occurs more often than previously recognized and patients are often misdiagnosed with type 2 diabetes. The purpose of this review is to provide a comprehensive summary of the prevalence, epidemiology, pathophysiology and future research aims of AP-related diabetes. In addition, we propose a screening and diagnostic algorithm to aid clinicians in providing better care for their patients.
