Mun EJ, Wagh MS. Recent advances and current challenges in endoscopic resection with the full-thickness resection device. World J Gastroenterol 2023; 29(25): 4009-4020 [PMID: 37476589 DOI: 10.3748/wjg.v29.i25.4009]
Corresponding Author of This Article
Mihir S Wagh, FACG, FASGE, MD, Professor, Interventional Endoscopy, Division of Gastroenterology, University of Colorado School of Medicine, 1635 Aurora Court, F735, Aurora, CO 80045, United States. mihir.wagh@cuanschutz.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jul 7, 2023; 29(25): 4009-4020 Published online Jul 7, 2023. doi: 10.3748/wjg.v29.i25.4009
Recent advances and current challenges in endoscopic resection with the full-thickness resection device
Elijah J Mun, Mihir S Wagh
Elijah J Mun, Division of Gastroenterology, University of Colorado School of Medicine, Aurora, CO 80045, United States
Mihir S Wagh, Interventional Endoscopy, Division of Gastroenterology, University of Colorado School of Medicine, Aurora, CO 80045, United States
Author contributions: Mun EJ contributed drafting of the manuscript; Wagh MS contributed critical review of the manuscript and endoscopic image acquisition.
Conflict-of-interest statement: Dr. Mun discloses no conflict of interest for this article; Dr. Wagh is consultant for Boston Scientific, Olympus, Medtronic, Fujifilm and ConMed.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mihir S Wagh, FACG, FASGE, MD, Professor, Interventional Endoscopy, Division of Gastroenterology, University of Colorado School of Medicine, 1635 Aurora Court, F735, Aurora, CO 80045, United States. mihir.wagh@cuanschutz.edu
Received: February 10, 2023 Peer-review started: February 10, 2023 First decision: March 15, 2023 Revised: March 27, 2023 Accepted: June 5, 2023 Article in press: June 5, 2023 Published online: July 7, 2023
Abstract
Endoscopic full-thickness resection (EFTR) has emerged as a viable technique in the management of mucosal and subepithelial lesions of the gastrointestinal tract (GIT) not amenable to conventional therapeutic approaches. While various devices and techniques have been described for EFTR, a single, combined full-thickness resection and closure device (full-thickness resection device, FTRD system, Ovesco Endoscopy AG, Tuebingen, Germany) has become commercially available in recent years. Initially, the FTRD system was limited to use in the colorectum only. Recently, a modified version of the FTRD has been released for EFTR in the upper GIT as well. This review provides a broad summary of the FTRD, highlighting recent advances and current challenges.
Core Tip: Endoscopic full-thickness resection (EFTR) is an emerging technique for tissue resection of lesions in the gastrointestinal tract (GIT) not amenable to conventional resection approaches. The novel full-thickness resection device (FTRD) is a combined full-thickness resection and closure device that allows for EFTR of lesions in the GIT. EFTR with FTRD is feasible, safe, and efficacious and should be considered as a viable option for resection of select lesions in the lower and upper GIT.
