Liu JB, Gu QB, Liu P. Inflammatory myofibroblastic tumor of the pancreatic neck misdiagnosed as neuroendocrine tumor: A case report. World J Gastroenterol 2023; 29(20): 3216-3221 [PMID: 37346157 DOI: 10.3748/wjg.v29.i20.3216]
Corresponding Author of This Article
Peng Liu, MD, Chief Doctor, Department of Radiology, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People’s Hospital), No. 61 Jiefang West Road, Changsha 410005, Hunan Province, China. lpradiology@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. May 28, 2023; 29(20): 3216-3221 Published online May 28, 2023. doi: 10.3748/wjg.v29.i20.3216
Inflammatory myofibroblastic tumor of the pancreatic neck misdiagnosed as neuroendocrine tumor: A case report
Jia-Bei Liu, Qian-Biao Gu, Peng Liu
Jia-Bei Liu, Department of Radiology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People’s Hospital, Changsha 410005, Hunan Province, China
Qian-Biao Gu, Peng Liu, Department of Radiology, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People’s Hospital), Changsha 410005, Hunan Province, China
Author contributions: Liu JB contributed to manuscript writing and editing, and data collection; Liu P and Gu QB contributed to conceptualization and supervision; and all authors have read and approved the final manuscript.
Supported bythe Clinical Medical Technology Innovation Guiding Project of Hunan Province, No. 2021SK50911; and Scientific Research Project of Hunan Health Commission, No. 202209010030.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Peng Liu, MD, Chief Doctor, Department of Radiology, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People’s Hospital), No. 61 Jiefang West Road, Changsha 410005, Hunan Province, China. lpradiology@163.com
Received: March 10, 2023 Peer-review started: March 10, 2023 First decision: April 14, 2023 Revised: April 21, 2023 Accepted: May 4, 2023 Article in press: May 4, 2023 Published online: May 28, 2023 Processing time: 76 Days and 22.2 Hours
Abstract
BACKGROUND
Inflammatory myofibroblastic tumor (IMT) is a relatively rare tumor. The global incidence of IMT is less than 1%. There is no specific clinical manifestation. It usually occurs in the lungs, but the pancreas is not the predilection site.
CASE SUMMARY
We present a case of a male patient, 51 years old, who was diagnosed with a pancreatic neck small mass on ultrasound one year ago during a physical examination. As he had no clinical symptoms and the mass was relatively small, he did not undergo treatment. However, the mass was found to be larger on review, and he was referred to our hospital. Since the primal clinical diagnosis was pancreatic neuroendocrine tumor, the patient underwent surgical treatment. However, the case was confirmed as pancreatic IMT by postoperative pathology.
CONCLUSION
Pancreatic IMT is relatively rare and easily misdiagnosed. We can better under-stand and correctly diagnose this disease by this case report.
Core Tip: Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor composed of spindle-shaped myofibroblasts accompanied by a mixed inflammatory infiltrate, and is particularly rare in the pancreas. The diagnosis of pancreatic IMT is made on the basis of histopathology and immunohistochemistry. Different lesions exhibit diverse biological characteristics, and there are several surgical treatment protocols. This case emphasizes the importance of correct preoperative diagnosis of IMT and reminds us to broaden our thinking in relation to the diagnosis of pancreatic lesions.
