Dolinger MT, Kayal M. Intestinal ultrasound as a non-invasive tool to monitor inflammatory bowel disease activity and guide clinical decision making. World J Gastroenterol 2023; 29(15): 2272-2282 [PMID: 37124889 DOI: 10.3748/wjg.v29.i15.2272]
Corresponding Author of This Article
Maia Kayal, MD, MS, Assistant Professor, Department of Medicine, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1069, New York, NY 10029, United States. maia.kayal@mountsinai.org
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Apr 21, 2023; 29(15): 2272-2282 Published online Apr 21, 2023. doi: 10.3748/wjg.v29.i15.2272
Intestinal ultrasound as a non-invasive tool to monitor inflammatory bowel disease activity and guide clinical decision making
Michael T Dolinger, Maia Kayal
Michael T Dolinger, Department of Pediatric Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States
Maia Kayal, Department of Medicine, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States
Author contributions: Dolinger MT and Kayal M contributed to the conception of the manuscript, Dolinger MT drafted manuscript; Kayal M edited the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maia Kayal, MD, MS, Assistant Professor, Department of Medicine, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1069, New York, NY 10029, United States. maia.kayal@mountsinai.org
Received: October 26, 2022 Peer-review started: October 26, 2022 First decision: December 12, 2022 Revised: January 19, 2023 Accepted: March 31, 2023 Article in press: March 31, 2023 Published online: April 21, 2023 Processing time: 169 Days and 21.8 Hours
Abstract
Intestinal ultrasound (IUS) is a non-invasive, real-time, cross-sectional imaging tool that can be used at the point-of-care to assess disease activity in patients with Crohn’s disease or ulcerative colitis. IUS promotes quick and impactful treatment decisions that can modify disease progression and enhance patient compliance. This review will summarize the technical aspects of IUS, the evidence to support the use of IUS in disease activity monitoring, the comparison of IUS to current standard of care monitoring modalities such as colonoscopy and calprotectin, and the optimal positioning of IUS in a tight-control monitoring strategy.
Core Tip: Intestinal ultrasound (IUS) is a non-invasive, real-time, cross-sectional imaging tool that is currently underutilized for direct disease activity monitoring in Crohn’s disease (CD) and ulcerative colitis (UC). IUS is the optimal point-of-care method to monitor disease activity in patients with CD or UC with excellent patient compliance and comparison to such traditional monitoring modalities as calprotectin, colonoscopy, and magnetic resonance enterography.
