Mao Q, Zhou MT, Zhao ZP, Liu N, Yang L, Zhang XM. Role of radiomics in the diagnosis and treatment of gastrointestinal cancer. World J Gastroenterol 2022; 28(42): 6002-6016 [PMID: 36405385 DOI: 10.3748/wjg.v28.i42.6002]
Corresponding Author of This Article
Lin Yang, MD, Professor, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, No. 63 Wenhua Road, Nanchong 637000, Sichuan Province, China. linyangmd@163.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 14, 2022; 28(42): 6002-6016 Published online Nov 14, 2022. doi: 10.3748/wjg.v28.i42.6002
Role of radiomics in the diagnosis and treatment of gastrointestinal cancer
Qi Mao, Mao-Ting Zhou, Zhang-Ping Zhao, Ning Liu, Lin Yang, Xiao-Ming Zhang
Qi Mao, Mao-Ting Zhou, Ning Liu, Lin Yang, Xiao-Ming Zhang, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Zhang-Ping Zhao, Department of Radiology, Panzhihua Central Hospital, Panzhihua 617000, Sichuan Province, China
Author contributions: Mao Q, Zhou MT, Zhao ZP, Liu N, Yang L, and Zhang XM contributed to this paper; Yang L and Zhang XM designed the overall concept and outline of the manuscript; Mao Q, Zhou MT, Zhao ZP, Liu N, and Yang L contributed to the writing and editing of the manuscript and reviewed the literature.
Supported bythe Project of the Medical Association of Sichuan Province, No. S20070; and Project of the City-University Science and Technology Strategic Cooperation of Nanchong City, No. 20SXQT0324.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lin Yang, MD, Professor, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, No. 63 Wenhua Road, Nanchong 637000, Sichuan Province, China. linyangmd@163.com
Received: August 25, 2022 Peer-review started: August 25, 2022 First decision: September 2, 2022 Revised: September 24, 2022 Accepted: October 27, 2022 Article in press: October 27, 2022 Published online: November 14, 2022 Processing time: 76 Days and 18.1 Hours
Abstract
Gastrointestinal cancer (GIC) has high morbidity and mortality as one of the main causes of cancer death. Preoperative risk stratification is critical to guide patient management, but traditional imaging studies have difficulty predicting its biological behavior. The emerging field of radiomics allows the conversion of potential pathophysiological information in existing medical images that cannot be visually recognized into high-dimensional quantitative image features. Tumor lesion characterization, therapeutic response evaluation, and survival prediction can be achieved by analyzing the relationships between these features and clinical and genetic data. In recent years, the clinical application of radiomics to GIC has increased dramatically. In this editorial, we describe the latest progress in the application of radiomics to GIC and discuss the value of its potential clinical applications, as well as its limitations and future directions.
Core Tip: In this editorial, we summarize the latest advances of radiomics in the field of gastrointestinal cancer diagnosis and treatment. Radiomics has great potential in precision treatment decision-making for gastrointestinal cancer. However, radiomics studies have had relatively marked heterogeneity in their workflow. In the future, it will be necessary to establish and promote an imaging data acquisition protocol, standardize the research workflow, and conduct multicenter prospective studies on quality control.
