Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4299
Peer-review started: January 17, 2022
First decision: March 8, 2022
Revised: March 22, 2022
Accepted: July 20, 2022
Article in press: July 20, 2022
Published online: August 21, 2022
Processing time: 211 Days and 5.3 Hours
Esophageal adenocarcinoma (EAC) and adenocarcinoma of the esophagogastric junction (EGJA) have long been associated with poor prognosis. With changes in the spectrum of the disease caused by economic development and demographic changes, the incidence of EAC and EGJA continues to increase, making them worthy of more attention from clinicians. For a long time, surgery has been the mainstay treatment for EAC and EGJA. With advanced techniques, endoscopic therapy, radiotherapy, chemotherapy, and other treatment methods have been developed, providing additional treatment options for patients with EAC and EGJA. In recent decades, the emergence of multidisciplinary therapy (MDT) has enabled the comprehensive treatment of tumors and made the treatment more flexible and diversified, which is conducive to achieving standardized and individualized treatment of EAC and EGJA to obtain a better prognosis. This review discusses recent advances in EAC and EGJA treatment in the surgical-centered MDT mode in recent years.
Core Tip: Worldwide, esophageal adenocarcinoma (EAC) and adenocarcinoma of the esophagogastric junction (EGJA) have long been associated with poor prognosis, and their incidence continues to increase. For a long time, surgery has been the mainstay treatment for EAC and EGJA. With the advent of advanced techniques, other treatment methods have been developed. In recent decades, the emergence of multidisciplinary therapy (MDT) has enabled the comprehensive treatment of tumors, which is conducive to achieving standardized and individualized treatment. This review discusses recent advances in EAC and EGJA treatment in the surgical-centered MDT mode in recent years.