Published online Apr 28, 2022. doi: 10.3748/wjg.v28.i16.1722
Peer-review started: December 1, 2021
First decision: December 26, 2021
Revised: January 7, 2022
Accepted: March 16, 2022
Article in press: March 16, 2022
Published online: April 28, 2022
Processing time: 143 Days and 23.3 Hours
Colon capsule endoscopy (CCE) was introduced nearly two decades ago. Initially, it was limited by poor image quality and short battery time, but due to technical improvements, it has become an equal diagnostic alternative to optical colonoscopy (OC). Hastened by the coronavirus disease 2019 pandemic, CCE has been introduced in clinical practice to relieve overburdened endoscopy units and move investigations to out-patient clinics. A wider adoption of CCE would be bolstered by positive patient experience, as it offers a diagnostic investigation that is not inferior to other modalities. The shortcomings of CCE include its inability to differentiate adenomatous polyps from hyperplastic polyps. Solving this issue would improve the stratification of patients for polyp removal. Artificial intelligence (AI) has shown promising results in polyp detection and characterization to minimize incomplete CCEs and avoid needless examinations. Onboard AI appears to be a needed application to enable near-real-time decision-making in order to diminish patient waiting times and avoid superfluous subsequent OCs. With this letter, we discuss the potential and role of AI in CCE as a diagnostic tool for the large bowel.
Core Tip: Colon capsule endoscopy (CCE) generates a vast amount of image material-currently, this material must be assessed manually. Artificial intelligence (AI) as an adjunct to CCE has been reported as having high accuracy for detecting colonic lesions. Future studies need to evaluate AI algorithms for estimating the likelihood of neoplasia and predicting which patients are most likely to benefit from CCE. Onboard capsule intelligence has the potential to generate result reports immediately after completed examinations.