Published online Jun 7, 2021. doi: 10.3748/wjg.v27.i21.2664
Peer-review started: March 17, 2021
First decision: April 5, 2021
Revised: April 14, 2021
Accepted: May 10, 2021
Article in press: May 10, 2021
Published online: June 7, 2021
Processing time: 70 Days and 12.7 Hours
Cystic pancreatic lesions involve a wide variety of pathological entities that include neoplastic and non-neoplastic lesions. The proper diagnosis, differentiation, and staging of these cystic lesions are considered a crucial issue in planning further management. There are great challenges for their diagnostic models. In our time, new emerging methods for this diagnosis have been discovered. Endoscopic ultrasonography-guided fine-needle aspiration cytology with chemical and molecular analysis of cyst fluid and EUS-guided fine needle-based confocal laser endomicroscopy, through the needle microforceps biopsy, and single-operator cho
Core Tip: Pancreatic cystic lesions are commonly recognized with increasing frequency and have become a more common finding in clinical practice. Today, there has been an increased incidence in cystic pancreatic lesions that have in turn caused a lot of diagnostic modalities to emerge. We discuss the various methods of the diagnosis of cystic pancreatic lesions and compare these modalities.