Retrospective Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2019; 25(9): 1080-1087
Published online Mar 7, 2019. doi: 10.3748/wjg.v25.i9.1080
Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness vs cost
Shana Kothari, Michael Kalinowski, Matthew Kobeszko, Tarek Almouradi
Shana Kothari, Michael Kalinowski, Matthew Kobeszko, Department of Internal Medicine, University of Illinois at Chicago - Advocate Christ Medical Center, Oak Lawn, IL 60453, United States
Tarek Almouradi, Department of Gastroenterology, Advocate Christ Medical Center, Oak Lawn, IL 60453, United States
Author contributions: All authors helped perform the research; Kothari S, Kalinowski M, Kobeszko M and Almouradi T contributed to drafting conception and design; Kothari S, Kalinowski M and Kobeszko M contributed to acquisition of data, analysis and interpretation of data, manuscript writing; Almouradi T approved the final version of the article to be published.
Informed consent statement: Patients were not required to give informed consent as this was a retrospective study and the research presented no risk of harm to subjects as all details were anonymized.
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shana Kothari MD, Resident Physician, Department of Internal Medicine, University of Illinois at Chicago - Advocate Christ Medical Center, 4440 95th St, Oak Lawn IL 60453, United States. shana.kothari@advocatehealth.com
Telephone: +1-630-8543856 Fax: +1-708-6842500
Received: November 6, 2018
Peer-review started: November 12, 2018
First decision: December 5, 2018
Revised: January 10, 2019
Accepted: January 26, 2019
Article in press: January 26, 2019
Published online: March 7, 2019
Processing time: 121 Days and 1.7 Hours
Abstract
BACKGROUND

Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. This imposes increased expenditure and cost in our healthcare system and does not improve hospital stay or management of AUP.

AIM

To assess the overutilization and associated cost of CT imaging among patients meeting diagnostic criteria for AUP.

METHODS

In this Institutional Review Board-approved retrospective, single-center study, we identified all adult patients admitted with AP from January 1, 2012 through October 1, 2017. Patients were identified via International Classification of Diseases (ICD-9) code for AP (577.0) and ICD-10 codes for different etiological AP (K85.9 unspecified, K85.0 idiopathic, K85.1 biliary, K85.2 alcohol-induced, K85.3 drug-induced, and K85.8 other). Diagnosis was confirmed by chart review using established non-imaging diagnostic criteria (presence of typical abdominal pain and elevated lipase or amylase greater than 3 times upper limit of normal). Ranson criteria and BISAP scores on presentation were calculated and patients that met scores less than or equal to 2 for both were included to suggest AUP. The utilization and cost of imaging in these patients were recorded.

RESULTS

Between January 2012 and October 2017, 1305 patients presented to the emergency department with AP, and 405 patients (31%) met our inclusion criteria for AUP (201 males, 204 females; mean age 49 years, range 18-98). Of those, 210 patients (51.85%) underwent CT imaging. One patient (0.47%) had evidence of pancreatic necrosis, one patient had cyst formation (0.47%), and the remaining 208 patients (99.05%) had either normal CT scan imaging or findings consistent with mild AP without necrosis. The average cost of CT scan imaging was $4510 with a total cost of $947056. Median length of hospitalization stay was 3 d among both groups. Combining Ranson’s Criteria and BISAP score identified AUP in our patient population with an accuracy of 99.5%.

CONCLUSION

CT imaging is unnecessary when AUP is diagnosed clinically and biochemically. Reducing overuse of diagnostic CT scans will decrease healthcare expenditure and radiation exposure to patients.

Keywords: Acute pancreatitis; Diagnostic criteria; Computed tomography imaging utilization; Quality improvement; Healthcare expenditure; Emergency department

Core tip: Guidelines indicate that routine use of imaging is unwarranted in patients with acute uncomplicated pancreatitis presenting with abdominal pain and increased serum amylase or lipase levels without signs of severe disease. This retrospective, single center study found that 51.85% of the study cohort underwent computed tomography imaging in the emergency department after having clinical and biochemical evidence of pancreatitis. The image findings did not impact hospital length of stay, and resulted in $947056 health expenditure. Quality improvement initiatives targeting overutilization of early imaging are needed to increase guideline adherence, reduce healthcare cost, and ultimately improve patient care.