Opinion Review
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2019; 25(25): 3108-3115
Published online Jul 7, 2019. doi: 10.3748/wjg.v25.i25.3108
Advanced imaging in surveillance of Barrett’s esophagus: Is the juice worth the squeeze?
Sara A Cerrone, Arvind J Trindade
Sara A Cerrone, Arvind J Trindade, Division of Gastroenterology, Long Island Jewish Medical Center, Zucker School of Medicine at Hofstra/Northwell, Northwell Health System, New Hyde Park, NY 11040, United States
Author contributions: All the authors contributed to conception and design; analysis and interpretation of the data; drafting of the article; critical revision of the article for important intellectual content; and final approval of the article.
Conflict-of-interest statement: The authors have declared no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Arvind J Trindade, MD, Director of Endoscopy, Division of Gastroenterology, Long Island Jewish Medical Center, Associate Professor of Medicine, Zucker School of Medicine at Hofstra/Northwell, Northwell Health System, 270-05 76th Avenue, New Hyde Park, NY 11040, United States. arvind.trindade@gmail.com
Telephone: +1-718-4707281 Fax: +1-718-4705509
Received: February 18, 2019
Peer-review started: February 18, 2019
First decision: April 30, 2019
Revised: May 8, 2019
Accepted: May 18, 2019
Article in press: May 18, 2019
Published online: July 7, 2019
Processing time: 138 Days and 5.9 Hours
Abstract

Esophageal cancer is on the rise. The known precursor lesion is Barrett’s esophagus (BE). Patients with dysplasia are at higher risk of developing esophageal cancer. Currently the gold standard for surveillance endoscopy involves taking targeted biopsies of abnormal areas as well as random biopsies every 1-2 cm of the length of the Barrett’s. Unfortunately studies have shown that this surveillance can miss dysplasia and cancer. Advanced imaging technologies have been developed that may help detect dysplasia in BE. This opinion review discusses advanced imaging in BE surveillance endoscopy and its utility in clinical practice.

Keywords: Barrett’s esophagus; Advanced imaging; Chromoendoscopy; Endomicroscopy

Core tip: Barrett’s esophagus (BE) is a precursor of esophageal cancer, the incidence of which is on the rise worldwide. Advanced imaging in BE includes dye chromoendoscopy, electronic chromoendoscopy narrow band imaging (NBI), confocal laser endomicroscopy and volumetric laser endomicroscopy (VLE). The decision to perform these procedures ultimately depends on if the benefit outweighs the cost and any added time performing the procedure. In our practice the added benefits of NBI and VLE outweighs the costs and added time and thus we have incorporated this into our Barrett’s surveillance routine.