Wang WJ, Xiao P, Xu HQ, Niu JQ, Gao YH. Growing burden of alcoholic liver disease in China: A review. World J Gastroenterol 2019; 25(12): 1445-1456 [PMID: 30948908 DOI: 10.3748/wjg.v25.i12.1445]
Corresponding Author of This Article
Yan-Hang Gao, MD, PhD, Chief Doctor, Department of Hepatology, First Hospital of Jilin University, Jilin University, No. 71, Xinmin Street, Changchun 130021, Jilin Province, China. yanhang@mail.jlu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Wen-Jun Wang, Peng Xiao, Hong-Qin Xu, Jun-Qi Niu, Yan-Hang Gao, Department of Hepatology, First Hospital of Jilin University, Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Gao YH and Niu JQ designed the research; Wang WJ and Xiao P performed the data analyses; Gao YH and Wang WJ drafted the manuscript; Gao YH and Xu HQ revised the paper; All authors approved the final version.
Supported bythe National Science and Technology Major Project, No. 2017ZX10202202 and No. 2018ZX10302206; the National Key Research Plan "Precision Medicine Research" Key Project, No. 2017YFC0908103; the National Natural Science Foundation of Jilin Province, No. 20160101097JC; the Program for JLU Science and Technology Innovative Research Team, No. 2017TD-08; and the Fundamental Research Funds for the Central Universities.
Conflict-of-interest statement: The authors have no potential conflicts of interest and received no financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yan-Hang Gao, MD, PhD, Chief Doctor, Department of Hepatology, First Hospital of Jilin University, Jilin University, No. 71, Xinmin Street, Changchun 130021, Jilin Province, China. yanhang@mail.jlu.edu.cn
Telephone: +86-431-81875121 Fax: +86-431-81875106
Received: January 24, 2019 Peer-review started: January 24, 2019 First decision: February 13, 2019 Revised: February 22, 2019 Accepted: March 1, 2019 Article in press: March 2, 2019 Published online: March 28, 2019 Processing time: 63 Days and 20.8 Hours
Abstract
Explosive economic growth and increasing social openness in China over the last 30 years have significantly boosted alcohol consumption, and consequently, the incidence of alcoholic liver disease (ALD) in China has increased. Because the epidemiologic and clinical features of ALD in the Chinese population may differ from those of the Caucasian population, this review describes the epidemiology, pathogenesis, genetic polymorphisms, diagnosis, and treatment of ALD in the Chinese population. This updated knowledge of ALD in China provides information needed for a global understanding of ALD and may help in the development of useful strategies for reducing the global ALD burden.
Core tip: Explosive economic growth and increasing social openness in China over the last 30 years have significantly boosted alcohol consumption, and consequently, the incidence of alcoholic liver disease (ALD) in China has increased. This review describes the epidemiology, pathogenesis, genetic polymorphisms, diagnosis, and treatment of ALD in the Chinese population, with the goal of supporting the development of useful strategies for reducing the global ALD burden.
