Published online Jul 7, 2018. doi: 10.3748/wjg.v24.i25.2776
Peer-review started: April 28, 2018
First decision: May 24, 2018
Revised: May 26, 2018
Accepted: June 9, 2018
Article in press: June 9, 2018
Published online: July 7, 2018
Liposarcoma of the stomach is extremely rare, and only 37 cases have been reported worldwide. We herein report two cases of liposarcoma of the stomach. The first patient was referred to our hospital with upper abdominal discomfort. The endoscopic examination revealed a tumor mass about 3 cm in diameter. The patient underwent a partial gastrectomy and had an uneventful recovery. The histopathological examination revealed a well-differentiated liposarcoma. The second patient had symptoms of upper abdominal discomfort combined with nausea and anorexia. Several palpable masses were found with endoscopy. Endoscopic submucosal dissection was the treatment used, and the postoperative course was uneventful. The histopathological diagnosis was a well-differentiated liposarcoma. The two patients did not undergo any adjuvant therapy. They are both currently in good condition without recurrence. Therefore, we believe that the outcome of liposarcoma of the stomach is positive, and surgical resection may be the first choice for treatment at present.
Core tip: Liposarcoma of the stomach is extremely rare, and only 37 cases have been reported in the literature. We herein report two cases and review the literature. These cases might contribute to improving our understanding of the etiology, diagnosis, treatment strategies, and outcome of liposarcoma of the stomach. This report can also serve as a reminder to gastroenterologists, surgeons, and pathologists who encounter liposarcoma of the stomach in their clinical practice.