Choi YJ, Kim DH, Han HS, Han JH, Son SM, Kim DS, Yun HY. Long-term survival after gastrectomy and metastasectomy for gastric cancer with synchronous bone metastasis. World J Gastroenterol 2018; 24(1): 150-156 [PMID: 29358891 DOI: 10.3748/wjg.v24.i1.150]
Corresponding Author of This Article
Hyo Yung Yun, MD, PhD, Professor, Department of Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine, 1 Chungdae-ro, Seowon-gu, Cheongju 28644, South Korea. yunhyo@chungbuk.ac.kr
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jan 7, 2018; 24(1): 150-156 Published online Jan 7, 2018. doi: 10.3748/wjg.v24.i1.150
Long-term survival after gastrectomy and metastasectomy for gastric cancer with synchronous bone metastasis
Young Jin Choi, Dae Hoon Kim, Hye Suk Han, Joung-Ho Han, Seung-Myoung Son, Dong Soo Kim, Hyo Yung Yun
Young Jin Choi, Dae Hoon Kim, Hyo Yung Yun, Department of Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, South Korea
Hye Suk Han, Joung-Ho Han, Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, South Korea
Seung-Myoung Son, Department of Pathology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, South Korea
Dong Soo Kim, Department of Orthopedics, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, South Korea
Author contributions: Choi YJ and Kim DH wrote the manuscript; Kim DS and Yun HY designed and revised the manuscript; Han HS, Han JH and Son SM participated in collection of the medical data; Choi YJ, Kim DH and Yun HY are responsible for accuracy of the case; all authors read and approved the final manuscript.
Informed consent statement: Informed consent was obtained from the patient for this case report.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hyo Yung Yun, MD, PhD, Professor, Department of Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine, 1 Chungdae-ro, Seowon-gu, Cheongju 28644, South Korea. yunhyo@chungbuk.ac.kr
Telephone: +82-43-2696032 Fax: +82-43-2666037
Received: October 30, 2017 Peer-review started: October 31, 2017 First decision: November 8, 2017 Revised: November 18, 2017 Accepted: November 27, 2017 Article in press: November 27, 2017 Published online: January 7, 2018 Processing time: 68 Days and 20.2 Hours
Abstract
Bone metastasis is a rare event in patients with gastric cancer, but pathologic fracture, paralysis, pain and hematological disorders associated with the bone metastasis may influence the quality of life. We report herein the case of a 53-year-old man who presented with primary remnant gastric cancer with bone metastasis. The patient requested further investigations after detection of a metastatic lesion in the 2nd lumbar vertebra during evaluation for back pain that had persisted for 3 mo. No other metastatic lesions were detected. He underwent total gastrectomy and palliative metastasectomy to aid in reduction of symptoms, and he received combination chemotherapy with tegafur (S-1) and cisplatin. The patient survived for about 60 mo after surgery. Currently, there is no treatment guideline for gastric cancer with bone metastasis, and we believe that gastrectomy plus metastasectomy may be an effective therapeutic option for improving quality of life and survival in patients with resectable primary gastric cancer and bone metastasis.
Core tip: Gastrectomy and metastasectomy may be an effective therapeutic option for improving quality of life and survival in selected gastric cancer patients with bone metastasis. Favorable factors, such as resectable solitary bone lesions, good performance status and normal serum carcinoembryonic antigen levels, should be utilized to stratify and select patients who will be good candidates for surgery.
