Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2017; 23(27): 4892-4896
Published online Jul 21, 2017. doi: 10.3748/wjg.v23.i27.4892
Endoscopic ultrasound-guided radiofrequency ablation in gastroenterology: New horizons in search
Satyarth Chaudhary, Si-Yu Sun
Satyarth Chaudhary, Department of Gastroenterology and Hepatology, Kidney Hospital and Lifeline Medical Institutions, Jalandhar, Punjab 144003, India
Si-Yu Sun, Endoscopy Center, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Author contributions: Both authors equally contributed to this paper with regard to conception and design of the study, literature review and analysis, drafting, critical revision and editing of the manuscript, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest exist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Si-Yu Sun, Professor, Endoscopy Center, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110004, Liaoning Province, China.
Telephone: +86-24-96615
Received: January 28, 2017
Peer-review started: February 9, 2017
First decision: April 10, 2017
Revised: April 30, 2017
Accepted: June 9, 2017
Article in press: June 12, 2017
Published online: July 21, 2017

Radiofrequency ablation (RFA) has been widely used for the treatment of various solid organ malignancies. Over the last decade, endosonographers have gradually shifted the application of RFA from porcine models to humans to treat a spectrum of diseases. RFA is performed in patients with pancreatic carcinoma who are not candidates for surgery. In this paper, we will discuss various indications for RFA, its procedural details and complications. At present, endoscopic ultrasound-guided RFA is gradually incorporated into the management of various diseases and opens a new avenue for disease treatment.

Keywords: Pancreatic carcinoma, Radiofrequency ablation

Core tip: Endoscopic ultrasound-guided radiofrequency ablation (RFA) is a rapidly emerging modality, whose application has shifted from porcine models to humans over the last decade. In this review, we provide details on the indications, thermokinetic principles and complications related to RFA, which should be judiciously applied in the management of various diseases.