Ha JY, Oh EH, Jung MK, Park SE, Kim JT, Hwang IG. Choroidal and skin metastases from colorectal cancer. World J Gastroenterol 2016; 22(43): 9650-9653 [PMID: 27920486 DOI: 10.3748/wjg.v22.i43.9650]
Corresponding Author of This Article
In Gyu Hwang, MD, PhD, Associate Professor, Department of Internal Medicine, Division of Hemato-oncology, Chung-Ang University College of Medicine, 224-1 Heukseok-dong, Dongjak-gu, Seoul 156-861, South Korea. hematoonco@naver.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 21, 2016; 22(43): 9650-9653 Published online Nov 21, 2016. doi: 10.3748/wjg.v22.i43.9650
Choroidal and skin metastases from colorectal cancer
Joo Young Ha, Edward Hynseung Oh, Moon Ki Jung, Song Ee Park, Ji Tak Kim, In Gyu Hwang
Joo Young Ha, Edward Hynseung Oh, Moon Ki Jung, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul 156-861, South Korea
Song Ee Park, In Gyu Hwang, Department of Internal Medicine, Division of Hemato-oncology, Chung-Ang University College of Medicine, Seoul 156-861, South Korea
Ji Tak Kim, Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul 156-861, South Korea
Author contributions: All authors contributed to acquisition of data, writing, and revision of this manuscript.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at Chung-Ang University College of Medicine.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of her protected health information.
Conflict-of-interest statement: All the authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: In Gyu Hwang, MD, PhD, Associate Professor, Department of Internal Medicine, Division of Hemato-oncology, Chung-Ang University College of Medicine, 224-1 Heukseok-dong, Dongjak-gu, Seoul 156-861, South Korea. hematoonco@naver.com
Telephone: +82-2-62991403 Fax: +82-2-62992114
Received: June 22, 2016 Peer-review started: June 24, 2016 First decision: August 8, 2016 Revised: August 17, 2016 Accepted: August 30, 2016 Article in press: August 30, 2016 Published online: November 21, 2016 Processing time: 148 Days and 23.6 Hours
Abstract
Choroidal and skin metastasis of colon cancer is rare. In women, the frequency of cutaneous metastasis from colon cancer as the primary lesion in is 9% and skin metastasis occurs in 0.81% of all colorectal cancers. We report a patient with colonic adenocarcinoma who presented with visual disorder in her right eye and scalp pain as her initial symptoms. Contrast-enhance orbital magnetic resonance imaging with fat suppression revealed an infrabulbar mass, and skin biopsy of the posterior parietal scalp confirmed adenocarcinoma. These symptoms were diagnosed as being caused by choroidal and skin metastases of colonic adenocarcinoma. We started palliative chemotherapy with oral capecitabine (1000 mg/m2, twice a day, on days 1-14) every 3 wk, which was effective at shrinking the brain masses and improving the visual disorder. This is the first report that capecitabine is effective at reducing a choroidal and cutaneous metastatic lesion from right-sided colorectal cancer.
Core tip: This case report describes a rare choroidal and skin metastasis of colon cancer and demonstrates that capecitabine is effective at reducing a choroidal and skin metastatic lesion from right-sided colorectal cancer.
