Lee SH, Lee TH, Jang SH, Choi CY, Lee WM, Min JH, Cho HD, Park SH. Ampullary neuroendocrine tumor diagnosed by endoscopic papillectomy in previously confirmed ampullary adenoma. World J Gastroenterol 2016; 22(13): 3687-3692 [PMID: 27053861 DOI: 10.3748/wjg.v22.i13.3687]
Corresponding Author of This Article
Tae Hoon Lee, MD, PhD, Division of Gastroenterology, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, 23-20 Bongmyung-Dong, Cheonan 330-721, South Korea. thlee9@schmc.ac.kr
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Apr 7, 2016; 22(13): 3687-3692 Published online Apr 7, 2016. doi: 10.3748/wjg.v22.i13.3687
Ampullary neuroendocrine tumor diagnosed by endoscopic papillectomy in previously confirmed ampullary adenoma
Seoung Ho Lee, Tae Hoon Lee, Si-Hyong Jang, Chi Young Choi, Won Myung Lee, Ji Hey Min, Hyun Deuk Cho, Sang-Heum Park
Seoung Ho Lee, Tae Hoon Lee, Chi Young Choi, Won Myung Lee, Ji Hey Min, Sang-Heum Park, Division of Gastroenterology, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan 330-721, South Korea
Si-Hyong Jang, Hyun Deuk Cho, Department of Pathology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan 330-721, South Korea
Author contributions: Lee SH, Choi CY, Lee WM and Min JH acquired data and performed the research; Lee TH performed endoscopic procedures; Jang SH and Cho HD advised pathologic findings; Lee SH and Lee TH wrote the manuscript; Lee TH and Park SH revised the article.
Supported by the Soonchunhyang University Research Fund.
Institutional review board statement: This case study was reviewed and approved by the Soonchunhyang University College of Medicine, Cheonan Hospital Institutional Review Board.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of her protected health information.
Conflict-of-interest statement: All the authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Tae Hoon Lee, MD, PhD, Division of Gastroenterology, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, 23-20 Bongmyung-Dong, Cheonan 330-721, South Korea. thlee9@schmc.ac.kr
Telephone: +82-41-5703662 Fax: +82-41-5745762
Received: November 2, 2015 Peer-review started: November 4, 2015 First decision: December 15, 2015 Revised: December 17, 2015 Accepted: December 30, 2015 Article in press: December 30, 2015 Published online: April 7, 2016 Processing time: 146 Days and 22.4 Hours
Abstract
Ampullary adenoma is a common indication for endoscopic papillectomy. Ampullary neuroendocrine tumor (NET) is a rare disease for which complete surgical resection is the treatment of choice. However, because of the morbidity and mortality associated with surgical resection, endoscopic papillectomy is increasingly used in selected cases of low grade, with no metastasis and no invasion of the pancreatic or bile duct. Also, confirmed and complete endoscopic resection of ampullary NET accompanied by adenoma has not been reported to date. We report herein a rare case of an ampullary NET accompanied with adenoma, which was successfully and completely resected via endoscopic papillectomy. Prior to papillectomy, this case was diagnosed as an ampullary adenoma.
Core tip: In selected cases without metastasis or invasion of the pancreatic and bile duct, endoscopic papillectomy can be a treatment of choice for ampullary neuroendocrine tumor (NET). To the best of our knowledge, the complete cure case of successful endoscopic papillectomy for ampullary NET accompanied with ampullary adenoma has not been reported in the English-language literature. This unusual ampullary NET accompanied with adenoma was successfully treated by endoscopic papillectomy.
