Monteiro S, de Castro FD, Carvalho PB, Moreira MJ, Rosa B, Cotter J. PillCam® SB3 capsule: Does the increased frame rate eliminate the risk of missing lesions? World J Gastroenterol 2016; 22(10): 3066-3068 [PMID: 26973404 DOI: 10.3748/wjg.v22.i10.3066]
Corresponding Author of This Article
Sara Monteiro, MD, Department of Gastroenterology, Hospital Senhora da Oliveira, Rua dos Cutileiros, Creixomil, 4835-044 Guimarães, Portugal. sara.s.o.monteiro@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letters To The Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Mar 14, 2016; 22(10): 3066-3068 Published online Mar 14, 2016. doi: 10.3748/wjg.v22.i10.3066
PillCam® SB3 capsule: Does the increased frame rate eliminate the risk of missing lesions?
Sara Monteiro, Francisca Dias de Castro, Pedro Boal Carvalho, Maria João Moreira, Bruno Rosa, José Cotter
Sara Monteiro, Francisca Dias de Castro, Pedro Boal Carvalho, Maria João Moreira, Bruno Rosa, José Cotter, Department of Gastroenterology, Hospital Senhora da Oliveira, Rua dos Cutileiros, Creixomil, 4835-044 Guimarães, Portugal
José Cotter, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal
José Cotter, ICVS/3B’s, PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal
Author contributions: Monteiro S and de Castro FD carried out the study and data analyses; Monteiro S drafted the manuscript; Carvalho PB participated in the design and coordination of the study; Rosa B and Moreira MJ conceived the study, participated in its design and coordination; Rosa B helped to draft the manuscript; Cotter J critically revised the manuscript and finally approved the version to be submitted; all authors read and approved the final manuscript.
Conflict-of-interest statement: The authors have no conflict of interest to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sara Monteiro, MD, Department of Gastroenterology, Hospital Senhora da Oliveira, Rua dos Cutileiros, Creixomil, 4835-044 Guimarães, Portugal. sara.s.o.monteiro@gmail.com
Telephone: +351-253-540330 Fax: +351-253-513592
Received: August 18, 2015 Peer-review started: August 18, 2015 First decision: September 9, 2015 Revised: October 2, 2015 Accepted: December 8, 2015 Article in press: December 8, 2015 Published online: March 14, 2016 Processing time: 199 Days and 15.9 Hours
Abstract
Since its emergence in 2000, small bowel capsule endoscopy (SBCE) has assumed a pivotal role as an investigation method for small bowel diseases. The PillCam® SB2-ex offers 12 h of battery time, 4 more than the previous version (SB2). Rahman et al recently found that the PillCam® SB2-ex has a significantly increased completion rate, although without higher diagnostic yield, compared with the SB2. We would like to discuss these somewhat surprising results and the new potentialities of the PillCam® SB3 regarding the diagnostic yield of small bowel studies. PillCam® SB3 offers improved image resolution and faster adaptable frame rate over previous versions of SBCE. We recently compared the major duodenal papilla detection rate obtained with PillCam® SB3 and SB2 as a surrogate indicator of diagnostic yield in the proximal small bowel. The PillCam® SB3 had a significantly higher major duodenal papilla detection rate than the PillCam® SB2 (42.7% vs 24%, P = 0.015). Thus, the most recent version of the PillCam® capsule, SB3, may increase diagnostic yield, particularly in the proximal segments of the small bowel.
Core tip: Rahman et al recently found that the 12 h PillCam® SB2-ex has a significantly increased completion rate, although without higher diagnostic yield, compared with the 8 h PillCam® SB2. We compared the major duodenal papilla detection rates between the PillCam® SB3 and SB2 as a surrogate indicator of diagnostic yield in the proximal small bowel. The PillCam® SB3 had a significantly higher major duodenal papilla detection rate than the PillCam® SB2 (42.7% vs 24%, P = 0.015). Thus, the most recent version of the PillCam® capsule, SB3, may increase diagnostic yield, particularly in the proximal segments of the small bowel.
