Lee J, Lee SW, Han SY, Baek YH, Kim SY, Rhyou HI. Rapidly aggravated skeletal muscle metastases from an intrahepatic cholangiocarcinoma. World J Gastroenterol 2015; 21(6): 1989-1993 [PMID: 25684968 DOI: 10.3748/wjg.v21.i6.1989]
Corresponding Author of This Article
Sung Wook Lee, MD, Department of internal medicine, Dong-A University, College of Medicine, 26 Daeshingongwonro, Seo-Gu, Busan 602-715, South Korea. sunglee@dau.ac.kr
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Feb 14, 2015; 21(6): 1989-1993 Published online Feb 14, 2015. doi: 10.3748/wjg.v21.i6.1989
Rapidly aggravated skeletal muscle metastases from an intrahepatic cholangiocarcinoma
Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou
Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea
Author contributions: Lee J and Lee SW designed the research; Lee J and Kim SY collected the patient's clinical data; Han SY and Baek YH analyzed the data; Lee J and Rhyou HI wrote the paper.
Supported by Dong-A University Hospital, Pusan, South Korea.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sung Wook Lee, MD, Department of internal medicine, Dong-A University, College of Medicine, 26 Daeshingongwonro, Seo-Gu, Busan 602-715, South Korea. sunglee@dau.ac.kr
Telephone: +82-51-240-2983 Fax: +82-51-242-5852
Received: June 26, 2014 Peer-review started: June 26, 2014 First decision: August 6, 2014 Revised: September 11, 2014 Accepted: October 14, 2014 Article in press: October 15, 2014 Published online: February 14, 2015 Processing time: 230 Days and 7.7 Hours
Abstract
We present a rare case of intrahepatic cholangiocarcinoma (ICC) with multiple skeletal muscle metastases. The patient was a 55-year-old Asian woman presenting with abdominal pain; abdominal and pelvic computed tomography and magnetic resonance cholangiopancreatography revealed an unresectable ICC with hepatic metastasis and metastastatic lymphadenopathy in the porto-caval area. After 3 mo of treatment with palliative radiotherapy and chemotherapy, magnetic resonance imaging of the thoracolumbar spine detected right psoas muscle and paraspinous muscle metastases. We performed an ultrasound-guided percutaneous fine-needle biopsy that confirmed a similar pattern of poorly differentiated adenocarcinoma. The patient treated with palliative chemotherapy and achieved 10 mo of survival. Here we report the first case quickly spread to multiple sites of muscle even though the three-month treatment, compare to the other cases reported muscle metastases at diagnosis.
Core tip: The case presented with multiple skeletal muscle metastases from an intrahepatic cholangiocarcinoma which only 5 cases have been reported so far.
