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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 21, 2015; 21(43): 12249-12260
Published online Nov 21, 2015. doi: 10.3748/wjg.v21.i43.12249
Recent aspects for disseminated carcinomatosis of the bone marrow associated with gastric cancer: What has been done for the past, and what will be needed in future?
Haruo Iguchi
Haruo Iguchi, Department of Gastroenterology, Shikoku Cancer Center, Matsuyama, Ehime 791-0280, Japan
Author contributions: Iguchi H wrote the manuscript.
Conflict-of-interest statement: The author has no conflict of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Haruo Iguchi, Department of Gastroenterology, Shikoku Cancer Center, Minami-Umemotomachi Ko 160, Matsuyama, Ehime 791-0280, Japan. higuchi@shikoku-cc.go.jp
Telephone: +81-899991111 Fax: +81-899991128
Received: April 27, 2015
Peer-review started: May 1, 2015
First decision: June 23, 2015
Revised: July 24, 2015
Accepted: October 23, 2015
Article in press: October 26, 2015
Published online: November 21, 2015
Processing time: 204 Days and 18.9 Hours
Abstract

Disseminated carcinomatosis of the bone marrow is characterized by widespread bone metastasis (bone marrow infiltration) from solid tumors with hematological disorders coexisted. This disease is frequently complicated with gastric cancer among solid tumors although its incidence is very rare. In recent years, technological innovations in diagnosis and treatment for cancer have remarkably improved, which made survival rates of various cancers prolonged. Prognosis of disseminated carcinomatosis of the bone marrow associated with gastric cancer, however, is still poor (less than a year), possibly because this disease has not been given attention due to low incidence. In this review, I summarize the results obtained for the past, and propose ways to improve the prognosis of this disease.

Keywords: Disseminated carcinomatosis of the bone marrow; Gastric cancer; Patogenesis; Diagnosis; Treatment

Core tip: Disseminated carcinomatosis of the bone marrow is characterized by widespread bone metastasis from solid tumors with hematological disorders coexisted. This disease is frequently complicated with gastric cancer among solid tumors although its incidence is very rare. Technological innovations in diagnosis and treatment for cancer have remarkably improved in recent years, however, prognosis of this disease associated with gastric cancer remains still very poor. In this review, I summarize the results obtained for the past, and propose ways to improve the prognosis of this disease associated with gastric cancer.